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Spermine alkaloids from Albizia adinocephala with activity against Plasmodium falciparum plasmepsin II. | LitMetric
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Spermine alkaloids from Albizia adinocephala with activity against Plasmodium falciparum plasmepsin II.

Simon P B Ovenden Shugeng Cao Chungyan Leong Horst Flotow Mahabir P Gupta Antony D Buss Mark S Butler

Phytochemistry

Centre for Natural Product Research, 59A Science Park Drive, The Fleming, Singapore Science Park, 118240, Singapore.

Published: May 2002

Crude MeOH extracts from the stem bark and leaves of a Panamanian specimen of Albizia adinocephala (Leguminosae) were found to inhibit the malarial enzyme plasmepsin II. Bioassay guided fractionation led to the isolation of two new bioactive spermine alkaloids, budmunchiamines L4 and L5.

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 Source
http://dx.doi.org/10.1016/s0031-9422(02)00081-xDOI Listing

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