We consider the oscillatory flow between time-periodically corotating cylinders, in the case of a two-frequency forcing. The angular velocity Omega(t) of the cylinders is the sum of a low-frequency omega(1) oscillation plus a harmonic frequency omega(2) oscillation at a lower amplitude, Omega(t)=Omega(1) cos(omega(1)t)+Omega(2) cos(omega(2)t). The temporal behavior of the secondary flow is characterized by ultrasound Doppler velocimetry. For a single-frequency forcing at omega(1), above a critical amplitude Omega(1), within one cycle, the secondary flow measurements exhibit a spikelike behavior with several successive growths, dampings, and periods of quietness. The effect of the superimposed omega(2) frequency is the following, although if alone it would be stable: to sharpen the spikes, restabilizing the flow for some intervals that exhibit secondary flow for the single forcing at omega(1); and to induce further secondary flow spikes during what is a quiescent stage in the single omega(1) frequency forcing case. Numerical calculations for the finite-gap quasisteady linear stability analysis are presented and provide a good prediction of the times of growth and damping of the secondary flow observed experimentally during a flow period.
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http://dx.doi.org/10.1103/PhysRevE.65.047301 | DOI Listing |
STAR Protoc
January 2025
Department of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden; Department of Surgical Sciences, Uppsala University, 75185 Uppsala, Sweden. Electronic address:
Here, we present a protocol for guiding tissue preparation and flow cytometric analysis in subcutaneous murine tumor models and secondary lymphoid organs. We describe steps for dissociating tumors, spleens, and lymph nodes to obtain single-cell suspensions. We then detail procedures for immune cell staining and analysis and gating strategies including the use of fluorescence-minus-one controls (FMOs).
View Article and Find Full Text PDFDose Response
January 2025
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Cytokinins are plant hormones that regulate cell growth and differentiation. In particular, zeatin (ZTN) delays cellular senescence of human fibroblasts and keratinocytes and exhibits anticancer activity. Chemotherapy-induced anemia is a major side effect of anticancer therapy secondary to premature senescence of red blood cells (RBCs).
View Article and Find Full Text PDFInt J Oncol
February 2025
Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Solute carrier family 25 member 1 (SLC25A1) affects lipid metabolism and energy regulation in multiple types of tumor cell, affecting their proliferation and survival. To the best of our knowledge, however, the impact of SLC25A1 on the proliferation and survival of esophageal squamous cell carcinoma (ESCC) cells has yet to be explored. Here, SLC25A1 expression was detected in ESCC tissues and cell lines.
View Article and Find Full Text PDFNeurocrit Care
January 2025
Divisions of Vascular Neurology and Neurocritical Care, Inova Fairfax Medical Campus, Inova Neuroscience and Spine Institute, 3300 Gallows Rd., Falls Church, VA, 22042 , USA.
Background: Acute ischemic stroke with medium and large vessel occlusion is a leading cause of morbidity and mortality, in which timely intervention with mechanical thrombectomy (MT) is crucial for restoring cerebral blood flow and improving patient outcomes. Effective analgosedation and hemodynamic management during MT are critical to patient outcomes and typically managed by anesthesia. Because of inconsistent anesthesia support at our institution, we implemented a dedicated neurocritical care rapid response team (NCC-RRT) to manage these aspects of care.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Radiology, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Background: Previous studies have shown that higher uterine artery pulsatility index (UtA-PI) values in early pregnancy have predictive value for the risk of preeclampsia (PE). However, the sensitivity and specificity of this marker remain controversial. This study aims to explore further the association between UtA-PI in early pregnancy and the incidence of preeclampsia.
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