The purpose of this paper is to review the mortality rate in patients with aortic stenosis, and the special subgroup of this pathology associated with left ventricular dysfunction and clinical data of heart failure. The left ventricular dysfunction is recognized by low aortic gradients, and differentiation must be made between reversible ventricular dysfunction, in which case the optimal treatment is surgery, and irreversible ventricular disfunction, since in these cases surgical treatment will have excessively high mortality rates and no benefit.
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J Clin Med
January 2025
Laboratory of Epidemiological and Clinical Cardiology, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Breast cancer is a prevalent malignancy with rising incidence globally. Advances in endocrine therapy have improved outcomes for premenopausal women with hormone receptor-positive breast cancer. However, these treatments may induce menopause-like states, potentially elevating cardiovascular risks, including left ventricular (LV) dysfunction.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Biostatistics, Faculty of Medicine, Bursa Uludag University, 16059 Bursa, Turkey.
Colorectal cancer is the second leading cause of cancer-related deaths in the U.S., and colonoscopy is a critical tool for colon cancer screening and diagnosis.
View Article and Find Full Text PDFBiomedicines
January 2025
Thoracic-Cardiovascular Department, Azienda Ospedaliero-Universitaria Maggiore della Carità, 28100 Novara, Italy.
Cardiomyopathy represents the most important life-limiting condition of Duchenne muscular dystrophy (DMD) patients after the age of 20. Genetic alterations in the DMD gene result in the absence of functional dystrophin protein, leading to skeletal/cardiac muscle impairment. The DMD incidence is one in 5000 live male births.
View Article and Find Full Text PDFBiomedicines
January 2025
Chair and Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.
: Anthracyclines remain a pivotal element of numerous tumor management regimens; however, their utilization is associated with a range of adverse effects, the most significant of which is cardiotoxicity. Research is constantly being conducted to identify substances that could be incorporated into ongoing cancer chemotherapy to mitigate anthracycline-induced cardiotoxicity. Recently, the apelinergic system has received a lot of attention in this field due to its involvement in cardiovascular regulation.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2025
Department of Sport, Exercise and Health Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
Breast cancer (BC) is the most common cancer among women, with an incidence of 85-94 per 100,000 people annually in Europe. Despite the increasing incidence of BC, advancements in early detection and novel therapeutic approaches have improved survival rates. However, adjuvant treatments are associated with side effects, including a reduction in the left ventricular ejection fraction (LVEF), which can result in severe cardiac damage and progress to heart failure.
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