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Comparison of clinical and laboratory data between hantavirus infection and leptospirosis: a retrospective case series study in southern Taiwan.
Trans R Soc Trop Med Hyg
December 2024
School of Medicine, Institute of Graduate, Center for Tropical Medicine and Infectious Disease Research, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Background: Leptospirosis (LS) and hantavirus (HV) are rodent-borne diseases and share similar clinical manifestations, posing diagnostic challenges.
Methods: This retrospective study compared clinical characteristics, laboratory data, complications and outcomes of 33 LS and nine HV cases in Kaohsiung, Taiwan, from 2006 to 2021.
Results: Both LS and HV diseases had high rates of acute kidney injury (84.
Acute Pancreatitis and Leukemoid Reaction as the Presenting Manifestation of Hemorrhagic Fever with Renal Syndrome: A Case Report.
Infect Drug Resist
November 2024
Department of Emergency, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, People's Republic of China.
Article Synopsis
- Hemorrhagic fever with renal syndrome (HFRS), caused by Orthohantavirus hantanense, presents with symptoms like fever and kidney issues, but can also involve rare conditions like acute pancreatitis and leukemoid reaction.
- A case study of a 20-year-old male showed severe symptoms that led to hospitalization and a positive HTNV antibody test, highlighting the challenges in diagnosing HFRS when symptoms are atypical.
- The study stresses the need for healthcare professionals to identify unusual HFRS symptoms early and use a comprehensive treatment approach to enhance patient outcomes, especially in areas where the disease is common.
Isolation and characterization of genetic variants of Orthohantavirus hantanense from clinical cases of HFRS in Jiangxi Province, China.
PLoS Negl Trop Dis
September 2024
Nanchang Key Laboratory of Microbial Resources Exploitation & Utilization from Poyang Lake Wetland, College of Life Sciences, Jiangxi Normal University, Nanchang, Jiangxi, China.
Article Synopsis
- Hemorrhagic fever with renal syndrome (HFRS) is a major public health issue in Jiangxi province, China, with identified genetic variants of Orthohantavirus hantanense (HTNV) in local rodents, prompting research on their link to human infections.
- The study confirmed HFRS cases via real-time RT-PCR, isolated HTNV from patient samples, and sequenced the genomes to understand the variants and their clinical implications.
- Findings showed HTNV RNA in 29% of suspected cases, with high occurrence of fever and thrombocytopenia, while severe kidney injury was noted in a smaller percentage, indicating distinct clinical presentations linked to local HTNV variants.
Identification of a Orthohantavirus strain by clinical metagenomics in Brazil.
Diagn Microbiol Infect Dis
December 2024
Hospital Israelita Albert Einstein, São Paulo, Brazil; LIM03/07 Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
We describe a case of a 33-year-old male presented with fever, myalgia, nausea, and asthenia for six days. The patient lived in a rural area. Initial hypotheses included arbovirus infection, viral hepatitis, and Lyme disease.
View Article and Find Full Text PDFHantavirus Cardiopulmonary syndrome: Another Reason to Avoid Mice.
J Investig Med High Impact Case Rep
August 2024
Community Hospital, Grand Junction, CO, USA.
Article Synopsis
- Hantavirus cardiopulmonary syndrome is a serious illness caused by exposure to rodent waste, which can lead to severe respiratory problems.
- A 24-year-old male presented to the emergency department with symptoms like cough, shortness of breath, and gastrointestinal issues, eventually developing acute respiratory distress syndrome (ARDS).
- Blood tests confirmed hantavirus infection, and the patient was treated with supportive care, leading to his recovery; this case underscores the need to consider hantavirus in patients showing specific critical symptoms like thrombocytopenia and ARDS.
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