Gabapentin attenuates superior oblique myokymia.

Purpose: To investigate therapeutic effects of oral gabapentin therapy on superior oblique myokymia.

Design: Observational case series with measurement of visual acuity and eye movements before, during, and after therapy.

Methods: Two adult patients with superior oblique myokymia, refractory to other therapies, were treated with gabapentin orally after informed consent was obtained. Eye movements were measured using the magnetic search coil technique.

Results: Superior oblique myokymia completely resolved after starting gabapentin.

Conclusion: Gabapentin may be an effective treatment for superior oblique myokymia; a double-blind study seems justified.