AI Article Synopsis
- The paper discusses ongoing research to find new and effective oxytocin antagonists.
- It highlights the development of benzofuran derivatives that show strong antagonist activity and favorable pharmacokinetic properties.
- The research also focuses on enhancing the effectiveness of these compounds in live subjects.
Article Abstract
The paper covers continuing efforts to discover novel, potent and selective oxytocin antagonists. Further benzofuran derivatives with potent oxytocin antagonist activity and good pharmacokinetic parameters are reported. Efforts to improve the in vivo activity of the series are described.
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| http://dx.doi.org/10.1016/s0960-894x(02)00160-9 | DOI Listing |
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