This study investigated the effectiveness of vegetated buffer strips for removing contaminants in runoff from grassed plots (slope 15%) after application of cattle slurry. Plots (8 x 8 m2 or 8 x 3 m2) received slurry or inorganic fertilizer, and then simulated rainfall (1, 7 and 21 days after slurry/fertilizer application); after each event, runoff and percolates were sampled at various distances downslope (2, 4, 6, and 8 m), and analysed for Cl-, Na+, K+ and faecal bacteria contents. Contaminant concentrations were markedly higher in runoff from the slurry-amended plots than in runoff from the fertiliser-amended plots. After the first rainfall event, some contaminant concentrations in runoff from the slurry-amended plots declined with distance downslope (i.e. with buffer strip width), supporting the relative efficacy of the strip for retaining pollutants. After the second and third rainfall events, by contrast, our results suggest remobilisation of contaminants retained during the first event. Faecal bacteria levels (especially streptococcus levels) remained high throughout the study, even in percolates and runoff collected 8 m downslope after the third rainfall event, and indeed even downslope of the adjacent fertilizer-amended plots (indicating lateral movement): this suggests that bacterial contamination may be the most significant risk arising from slurry application.
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http://dx.doi.org/10.1016/s0960-8524(01)00183-3 | DOI Listing |
Commun Biol
January 2025
State Key Laboratory of Biocontrol, School of Marine Sciences, Sun Yat-sen University, Guangzhou, China.
Global warming has threatened all-rounded hierarchical biosphere by reconstructing eco-structure and bringing biodiversity variations. Pacific white shrimp, a successful model of worldwide utilizing marine ectothermic resources, is facing huge losses due to multiple diseases relevant to intestinal microbiota (IM) dysbiosis during temperature fluctuation. However, how warming mediates shrimp health remains poorly understood.
View Article and Find Full Text PDFGut Microbes
December 2025
Microbiome-Host Interactions, Institut Pasteur, Université Paris Cité, INSERM U1306, CNRS UMR6047, Paris, France.
Metabolic syndrome is, in humans, associated with alterations in the composition and localization of the intestinal microbiota, including encroachment of bacteria within the colon's inner mucus layer. Possible promoters of these events include dietary emulsifiers, such as carboxymethylcellulose (CMC) and polysorbate-80 (P80), which, in mice, result in altered microbiota composition, encroachment, low-grade inflammation and metabolic syndrome. While assessments of gut microbiota composition have largely focused on fecal/luminal samples, we hypothesize an outsized role for changes in mucus microbiota in driving low-grade inflammation and its consequences.
View Article and Find Full Text PDFEur J Pharmacol
January 2025
School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, 11800, Penang, Malaysia. Electronic address:
Microbiota encompasses a diverse array of microorganisms inhabiting specific ecological niches. Gut microbiota significantly influences physiological processes, including gastrointestinal motor function, neuroendocrine signalling, and immune regulation. They play a crucial role in modulating the central nervous system and bolstering body defence mechanisms by influencing the proliferation and differentiation of innate and adaptive immune cells.
View Article and Find Full Text PDFIntroduction: Elexacaftor/tezacaftor/ivacaftor (ETI) has shown significant improvements in pulmonary and nutritional status in persons with cystic fibrosis (pwCF). Less is known about the extrapulmonary impact of ETI and effects on airway microbiology, lung clearance index (LCI) and fraction of exhaled nitric oxide (FeNO).
Methods: A multicentre prospective observational trial, including 79 pwCF ≥ 18 years eligible for ETI.
Nat Commun
January 2025
Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Gut microbiota disruptions after allogeneic hematopoietic cell transplantation (alloHCT) are associated with increased risk of acute graft-versus-host disease (aGVHD). We designed a randomized, double-blind placebo-controlled trial to test whether healthy-donor fecal microbiota transplantation (FMT) early after alloHCT reduces the incidence of severe aGVHD. Here, we report the results from the single-arm run-in phase which identified the best of 3 stool donors for the randomized phase.
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