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Acute promyelocytic leukemia presenting as isolated femoral granulocytic sarcoma.
Turk J Pediatr
February 2025
Department of Pediatrics, Faculty of Medicine, KTO University, Konya, Türkiye.
Background: Granulocytic sarcoma (GS), or myeloid sarcoma or chloroma, is a tumoral mass containing myeloblasts and immature granulocytes in an anatomic site other than the bone marrow. GS is very rare in children with acute promyelocytic leukemia (APL). This case report presents a rare case of GS manifesting as a solitary bone mass.
View Article and Find Full Text PDFSurface triggering receptor expressed on myeloid cells-1 (sTREM1) in critically ill children: a prospective observational controlled study.
Turk J Pediatr
February 2025
Department of Pediatrics, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
Background: In children admitted to the pediatric intensive care unit (PICU), early detection of risk factors and alarming indicators improves the prognosis and may even save lives. Several prognostic markers and scores have been studied in children who are seriously ill. Recently, surface triggering receptor expressed on myeloid cells-1 (sTREM1) has been studied in many infectious and non-infectious settings; however, there is little information on critically ill children.
View Article and Find Full Text PDFApplication of Surgical Adhesive Reduces Ureteroureterostomy Leakage.
Cureus
February 2025
Surgery, Texas College of Osteopathic Medicine, Fort Worth, USA.
Their close proximity to abdominal structures and organs places the ureters at risk of iatrogenic injury during abdominal and pelvic surgical procedures. Ureteroureterostomy is the mainstay intervention for the repair of the proximal and middle ureter. However, the anastomosis may be subject to leakage, leading to potentially serious complications, including urinary tract infection, peritonitis, sepsis, and kidney damage.
View Article and Find Full Text PDFDiagnostic Performance of Monocyte Distribution Width for the Detection of Sepsis: A Systematic Review and Meta-Analysis.
J Am Coll Emerg Physicians Open
April 2025
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Objectives: To aggregate literature on the diagnostic performance of monocyte distribution width (MDW) for sepsis detection among adults in the emergency department and inpatient settings.
Methods: We searched the MEDLINE, EMBASE, SCOPUS, and Cochrane databases for studies evaluating MDW for sepsis diagnosis in adults in the hospital setting through October 19, 2024. Two authors (G.
Specific immune landscape of heatstroke distinguished from sepsis and aseptic inflammation.
Int J Med Sci
March 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
Heatstroke is associated with immune system disturbances, which was similar to sepsis and aseptic inflammation. This study characterized the immune landscape of heatstroke and compared it to sepsis or aseptic inflammation in order to identify heatstroke-specific characteristics. We prospectively recruited 40 patients with heatstroke as well as the same number of age- and sex-matched healthy controls, patients with sepsis, or cardiopulmonary bypass-induced aseptic inflammation.
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