[Mineralization of the dental pulp: contributions of tissue engineering to tomorrow's therapeutics in odontology].

Pathol Biol (Paris)

Laboratoire biologie et physiopathologie crâniofaciales EA 2496, faculté de chirurgie dentaire, université Paris V, 1, rue Maurice Arnoux, 92120 Montrouge, France.

Published: April 2002

When bioactive molecules such as bone sialoprotein (BSP), bone morphogenetic protein-7 (BMP-7, also termed OP-1) and chondrogenic Inducing Agents (CIA, A+4 and A-4) were implanted in the pulp of the first upper molars, mineralizations were induced. They were either limited to the formation of a reparative dentinal bridge closing the pulpal wound (CIA A+4), or filled the mesial part of the coronal pulp (BSP), or filled totally the pulp located in the root canal (BMP-7 and CIA A-4). Consequently, these molecules may change in the next future the every day practice in dentistry.

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Source
http://dx.doi.org/10.1016/s0369-8114(02)00288-2DOI Listing

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