AI Article Synopsis
- A study compared the effectiveness and safety of remifentanil combined with either desflurane or sevoflurane against a traditional method using alfentanil and desflurane in female patients.
- A total of 45 patients were divided into three groups, receiving different combinations of anesthetics after being induced with propofol.
- Overall, the two remifentanil groups had similar numbers of surgical responses and recovery times, while all groups showed a high rate of postoperative side effects, but patient satisfaction levels were comparable across the groups.
Article Abstract
We performed a prospective, randomized study comparing the efficacy and safety of the combination of remifentanil and the newer volatile anaesthetics desflurane and sevoflurane with a conventional anaesthetic technique using alfentanil and desflurane. Forty five ASA class I or II female patients were randomly assigned to one of three groups. Following induction with propofol patients received a continuous infusion of remifentanil in combination with either 0.5 MAC desflurane (n = 15) or sevoflurane (n = 15), a third group (n = 15) received 1 MAC of desflurane with bolus doses of alfentanil for maintenance of anaesthesia. Remifentanil infusion and alfentanil (bolus) were titrated to responses to surgical stimuli while the concentration of volatile agents was kept unchanged. The number of responses to surgical stimuli was similar in the two remifentanil groups and higher in the alfentanil-desflurane group. Recovery times were similar in all groups. The incidence of postoperative side effects was high in the three groups. No awareness occurred and patient satisfaction in the two remifentanil groups was comparable to the conventional anaesthetic technique.
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