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Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1).
J Nat Prod
December 2007
SW Center for Natural Products Research and Commercialization, Office of Arid Lands Studies, College of Agriculture and Life Sciences, The University of Arizona, Tucson, AZ 85706-6800, USA.
Four new diene valepotriates, sorbifolivaltrates A-D ( 1- 4), and the known compounds isovaltrate ( 5), valtrate ( 6), seneciovaltrate ( 7), valtrate hydrine B3 ( 8), and valtrate hydrine B7 ( 9), have been isolated by bioassay-guided fractionation of the cytotoxic hexanes and methyl ethyl ketone crude extracts of the aerial parts of Valeriana sorbifolia occurring in the Sonoran desert. The structures of 1- 4 were determined on the basis of their high-resolution mass spectrometric and NMR spectroscopic data. All compounds exhibited weak to moderate cytotoxicity against the human metastatic prostate cancer cell line, PC-3M.
View Article and Find Full Text PDF[Interspecific and intraspecific comparison of valepotrates contents in three Valeriana plants].
Zhong Yao Cai
April 2002
School of Pharmacy, Second Military Medical University, Shanghai 200433.
Objective: To compare the contents of three valepotrates intraspecifically and intraspecifically in three medicinal Valeriana plants grown in different areas in China.
Methods: The method of RE-HPLC was adopted.
Results: The results showed that the contents of three valepotriates in Valeriana jatamansi Jones, V.
HPLC analysis of valepotriates in the north american genera plectritis and valeriana.
Planta Med
February 1984
Institut für Pharmazeutische Biologie, Universität Heidelberg, Heidelberg, FRG.
Reversed phase HPLC has been applied to the isolation and quantitative distribution of valepotriates in roots and aerial parts of species and subspecies of the North American Genus PLECTRITIS (Valerianaceae) and in VALERIANA SITCHENSIS ssp. SCOULERI (Valerianaceae). A semipreparative Ultrasphere ODS column was used for separation and detection of small quantities of valepotriates in crude plant extracts.
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