Stereotypy in neocortical microcircuits.

Trends Neurosci

Department of Neurobiology, The Weizmann Institute of Science, 76100, Rehovot, Israel.

Published: May 2002

AI Article Synopsis

  • The debate on neocortical function revolves around how consistently microcircuits are organized, with "stereotypy" indicating a uniform structure and function.
  • This uniformity is often attributed to shared genetic influences and similar environmental factors, while "uniqueness" arises from genetic differences and varying conditions.
  • The idea of stereotypy supports a deterministic view of how neuronal microcircuits develop and how their specific structures relate to their functions.

Article Abstract

A central debate regarding neocortical function concerns the degree to which the underlying microcircuitry is stereotypically organized. Stereotypy reflects invariance in structure and function, as a result of common genetic templates and environmental conditions, whereas uniqueness can be caused by genetic variations, differences in environmental conditions as well as random processes. Stereotypy is an appealing concept because it provides strong support for determinism in the formation of neuronal microcircuits and in the relationship between their specific structure and function.

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Source
http://dx.doi.org/10.1016/s0166-2236(02)02151-3DOI Listing

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