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Supporting implementation of universal prevention initiatives in K-12 schools: impacts on fidelity through organizational readiness and team functioning in a cluster-randomized trial.
Implement Sci Commun
January 2025
Center for School and Community Partnerships, Boise State University, Boise, ID, USA.
Background: Rural School Support Strategies (RS3) is a bundle of implementation supports (including training, technical assistance, and a virtual learning collaborative) designed for the scale-up of universal prevention initiatives. This study addresses mechanisms of action, exploring whether positive effects of RS3 on implementation fidelity are attributable to improvements in functioning of school implementation teams, and increases in organizational readiness.
Methods: Data are from a cluster-randomized hybrid Type 3 implementation-effectiveness trial of RS3 among rural Idaho schools implementing Positive Behavioral Interventions and Supports (PBIS).
Effect of PCSK9 inhibitor on early neurological deterioration in acute ischemic stroke patients with a history of coronary heart disease: a study protocol for a randomized controlled trial in Dalian, China.
Trials
January 2025
Department of Neurology, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Background: Early neurological deterioration (END) is a critical determinant influencing the short-term prognosis of acute ischemic stroke (AIS) patients and is associated with increased mortality rates among hospitalized individuals. AIS frequently coexists with coronary heart disease (CHD), complicating treatment and leading to more severe symptoms and worse outcomes. Shared risk factors between CHD and AIS, especially elevated low-density lipoprotein cholesterol (LDL-C), contribute to atherosclerosis and inflammation, which worsen brain tissue damage.
View Article and Find Full Text PDFTibial stem extension versus standard configuration in primary cemented total knee arthroplasty: systematic review and meta-analysis.
J Orthop Surg Res
January 2025
Department of Epidemiology, School of Health, Mashhad University of Medical Science, Mashhad, Iran.
Background: In order to increase the stability of tibial component in total knee arthroplasty (TKA), intramedullary stem extensions (SE) have been developed. The aim of this systematic review and meta-analysis is to address the critical knowledge gap on post-operative outcomes and complications rate comparison between tibial component with SE compared to the tibial component standard configuration (SC) in primary cemented TKA.
Methods: We conducted a comprehensive search of online databases, including Pubmed, Embase, ISI Web of science, Cochrane Library, and Scopus, using the following MeSH terms, (total knee arthroplasty) OR (TKA) OR (total knee replacement) AND (Tibial stem) OR (stem extension) OR (long stem).
Open-label randomised clinical trial investigating whether robot-assisted kidney transplantation can reduce surgical complications compared to open kidney transplantation (ORAKTx): study protocol for a randomised clinical trial.
Trials
January 2025
Urological Research Unit, Department of Urology, Centre for Cancer and Organ Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Background: Kidney transplantation is the ultimate treatment for end-stage kidney disease. Function of the kidney graft is not only dependent on medical factors but also on a complication-free surgical procedure. In the event of major surgical complications, the kidney graft is potentially lost and the patient will return to the waiting list which may be long.
View Article and Find Full Text PDFThe development of a decision support tool in the prehospital setting for acute chest pain - a study protocol for an observational study (BRIAN2).
Scand J Trauma Resusc Emerg Med
January 2025
PreHospen-Centre for Prehospital Research, Faculty of Caring Science, Work Life and Social Welfare, University of Borås, Borås, Sweden.
Introduction: Chest pain is one of the most common reasons for contacting the emergency medical services (EMS). It is difficult for EMS personnel to distinguish between patients suffering from a high-risk condition in need of prompt hospital care and patients suitable for non-conveyance. A vast majority of patients with chest pain are therefore transported to the emergency department (ED) for further investigation even if hospital care is not necessary.
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