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Polyphenol metabolomics reveals the applications and prospects of polyphenol-rich plants in natural dyes.
For Res (Fayettev)
December 2024
State Key Laboratory of Tree Genetics and Breeding, Chinese Academy of Forestry, Beijing 100091, China.
Polyphenols, as one of the primary compounds produced by plant secondary metabolism, have garnered considerable attention because of their non-toxic, environmentally friendly, and biodegradable properties, as well as their notable medicinal value. This study presents a metabolomic analysis of polyphenols from 11 woody plants, including , , and , investigating a total of 40 polyphenolic metabolites. A differential metabolite dynamics map highlighted the five most differentiated substances among the 11 plants, including vitexin, dihydromyricetin, genistin, resveratrol, and isorhamnetin.
View Article and Find Full Text PDFCross-Sectional Validation of an Automated Lesion Segmentation Software in Multiple Sclerosis: Comparison with Radiologist Assessments.
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology, Medical University of South Carolina, Charleston, SC, USA (MVS, HRC, WD, JHC, JAC, MGM, STS, DRR), College of Medicine, Medical University of South Carolina, Charleston, SC, USA (HW, EY).
Background And Purpose: Magnetic Resonance Imaging is widely used to assess disease burden in multiple sclerosis (MS). This study aimed to evaluate the effectiveness of a commercially available k-nearest neighbors (k-NN) software in quantifying white matter lesion (WML) burden in MS. We compared the software's WML quantification to expert radiologists' assessments.
View Article and Find Full Text PDFExpansion of a conserved architecture drives the evolution of the primate visual cortex.
Proc Natl Acad Sci U S A
January 2025
Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104.
Human brain evolution is marked by a disproportionate expansion of cortical regions associated with advanced perceptual and cognitive functions. While this expansion is often attributed to the emergence of novel specialized brain areas, modifications to evolutionarily conserved cortical regions also have been linked to species-specific behaviors. Distinguishing between these two evolutionary outcomes has been limited by the ability to make direct comparisons between species.
View Article and Find Full Text PDFDynamical properties of the composed Logistic-Gauss map.
Chaos
January 2025
Physics Institute, University of São Paulo-USP, São Paulo, SP 05508-090, Brazil.
This study focuses on the analysis of a unique composition between two well-established models, known as the Logistic-Gauss map. The investigation cohesively transitions to an exploration of parameter space, essential for unraveling the complexity of dissipative mappings and understanding the intricate relationships between periodic structures and chaotic regions. By manipulating control parameters, our approach reveals intriguing patterns, with findings enriched by extreme orbits, trajectories that connect local maximum and minimum values of one-dimensional maps.
View Article and Find Full Text PDFDevelopment of Personas and Journey Maps for Artificial Intelligence Agents Supporting the Use of Health Big Data: Human-Centered Design Approach.
JMIR Form Res
January 2025
Big Data Convergence and Open Sharing System, Seoul National University, Seoul, Republic of Korea.
Background: The rapid proliferation of artificial intelligence (AI) requires new approaches for human-AI interfaces that are different from classic human-computer interfaces. In developing a system that is conducive to the analysis and use of health big data (HBD), reflecting the empirical characteristics of users who have performed HBD analysis is the most crucial aspect to consider. Recently, human-centered design methodology, a field of user-centered design, has been expanded and is used not only to develop types of products but also technologies and services.
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