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Dear Editor, The costs of antipsychotic drugs (APDs) used in the treatment of mental disorders with psychosis are mentioned in treatment guidelines (APA 2021, NICE 2014). While the American Psychiatric Association guideline states that every specialist should make decisions according to the rules and conditions of their country and their region, the National Institute of Health and Clinical Excellence guideline emphasizes that drug costs must be taken into consideration in the treatment process. Classical or first-generation antipsychotic drugs (FAPDs) are relatively cheaper in terms of sales prices compared to atypical or second-generation antipsychotic drugs (SAPDs) with a slightly different effect mechanism.
View Article and Find Full Text PDFZuclopenthixol dihydrochloride for schizophrenia.
Cochrane Database Syst Rev
November 2017
Sheffield Health and Social Care, NHS Foundation Trust, Fulwood House, Old Fulwood Road, Sheffield, UK, S10 3TH.
Background: Oral zuclopenthixol dihydrochloride (Clopixol) is an anti-psychotic treatment for people with psychotic symptoms, especially those with schizophrenia. It is associated with neuroleptic malignant syndrome, a prolongation of the QTc interval, extra-pyramidal reactions, venous thromboembolism and may modify insulin and glucose responses.
Objectives: To determine the effects of zuclopenthixol dihydrochloride for treatment of schizophrenia.
Neuroleptic malignant syndrome in adolescents: four probable cases in the Western Cape.
S Afr Med J
May 2011
Lentegeur Hospital, Mitchell's Plain, Cape Town.
Background: Neuroleptic malignant syndrome (NMS) is a rare side-effect of neuroleptic medication. Most NMS reports have been on adults, and the incidence in children and adolescents is unknown.
Objective: This report reviews cases of NMS to highlight possible risk factors for the development of NMS in adolescents.
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