Steaming ginseng at high temperature increased its cytotoxicity to SK-Hep-1 hepatoma cancer cells. HPLC separation and fractionation followed by MTT assay revealed that ginsenosides Rg3, Rg5, Rk1, Rs5, and Rs4 are the active principles. Their 50% growth inhibition concentration (GI50) values were 41, 11, 13, 37, and 13 microM, respectively. Cisplatin had a GI50 of 84 microM in the same assay conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.50.538 | DOI Listing |
Publication Analysis
Top Keywords
cytotoxic dammarane
4
dammarane glycosides
4
glycosides processed
4
processed ginseng
4
ginseng steaming
4
steaming ginseng
4
ginseng high
4
high temperature
4
temperature increased
4
increased cytotoxicity
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!