Australia ranks highly internationally for cancer control, in part because cancer registries provide comprehensive national incidence and mortality and other cancer data annually. This has facilitated short- and long-term planning over the last quarter of a century. For example, male death rates from lung cancer in Australia peaked around 1985 and are now falling steeply, whereas female rates are still rising. In women, cervical cancer incidence and mortality have fallen owing to cervical screening over the last quarter of a century. Breast cancer mortality is now trending downwards after a half-century plateau, probably because of better treatment protocols. Cancer registry based State and national population treatment surveys over the last 15 years have identified both deficiencies and strengths in evidenced-based treatment of cancer in Australia. For example, in the State of Victoria, 5-yearly population based breast cancer treatment surveys have shown that the proportion of women who had a mastectomy versus a lumpectomy as their primary surgical operation fell from 78% in 1986 to 47% 1995. All Australians are covered by a universal health care system. Therefore, socio-economic status is not a barrier to accessing high quality cancer control, whether it be prevention, screening, treatment or education. In addition, non-government organizations (NGOs) specializing in cancer control have been providing free or highly subsidized support services to patients and their families for over half a century in most states. These NGOs have also been very active in public education about cancer, especially cancer prevention.
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http://dx.doi.org/10.1093/jjco/hye121 | DOI Listing |
Front Biosci (Landmark Ed)
November 2024
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 230022 Hefei, Anhui, China.
Background: Aneuploidy is crucial yet under-explored in cancer pathogenesis. Specifically, the involvement of brain expressed X-linked gene 4 () in microtubule formation has been identified as a potential aneuploidy mechanism. Nevertheless, 's comprehensive impact on aneuploidy incidence across different cancer types remains unexplored.
View Article and Find Full Text PDFProstate Cancer
December 2024
Department of Histopathology and Cytology, Faculty of Medical Laboratory Sciences, Al-Neelain University, Khartoum, Sudan.
Prostate cancer is the most common noncutaneous malignancy among men worldwide, including in Sudan, where it represents a significant public health challenge. CD147, a transmembrane glycoprotein implicated in tumor progression, invasion, and metastasis, has shown potential as a prognostic biomarker in various cancers. This retrospective case-control study aimed to evaluate CD147 expression in prostate adenocarcinoma among Sudanese men and its association with tumor grade.
View Article and Find Full Text PDFIndian J Orthop
January 2025
Department of Orthopedics and Traumatology, Abdurrahman Yurtaslan Training and Research Hospital, Ankara, Turkey.
Background: Soft-tissue sarcoma involving the popliteal fossa remains challenging because it is difficult to achieve wide margins with limb salvage in this location. Adjuvant therapy is frequently necessary, and limb function can be adversely affected. We reviewed our experience with these tumors.
View Article and Find Full Text PDFInt J Ment Health Addict
December 2024
Department of Psychology, University of Waterloo, Waterloo, ON, Canada.
This study examined differences in quit attempts, 1-month quit success, and vaping status at follow-up among a cohort of 3709 daily smokers with and without depression, anxiety, and regular alcohol use who participated in both the 2018 and 2020 International Tobacco Control Four Country Smoking and Vaping (ITC 4CV) Surveys. At baseline, a survey with validated screening tools was used to classify respondents as having no, or one or more of the following: 1) depression, 2) anxiety, and 3) regular alcohol use. Multivariable adjusted regression analyses were used to examine whether baseline (2018) self-report conditions were associated with quit attempts; quit success; and vaping status by follow-up (2020).
View Article and Find Full Text PDFFront Public Health
December 2024
School of Preventive Medicine, Shandong First Medical University (Institute of Radiation Medicine, Shandong Academy of Medical Sciences), Jinan, Shandong, China.
Background: Radon, a colorless and odorless radioactive gas, poses serious health risks. It is the second leading cause of lung cancer and notably increases lung cancer risk in smokers. Although previous epidemiological studies have mainly examined lung cancer rates in miners, the effects of radon on genomic stability and its molecular mechanisms are not well understood.
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