Background: Mean left atrioventricular plane displacement is strongly related to prognosis in patients with heart failure. We aimed to examine its value for prognostication and risk stratification in patients hospitalised for acute myocardial infarction.

Methods And Results: Left atrioventricular plane displacement was assessed by echocardiography in 271 consecutive patients with acute myocardial infarction. Mean prospective follow-up was 628 days. Atrioventricular plane displacement was readily assessed in all patients and was significantly lower in patients who died (n=41, 15.1%) compared to the survivors: 8.2(5.6) v. 10.0(5.5) mm, P<0.0001. Overall mortality was 31.3% in the lowest quartile with regard to atrioventricular plane displacement (<8.00 mm) and 10.1% in the combined upper three quartiles. Thus, the hazard ratio for an atrioventricular plane displacement <8.0 mm compared to 8 mm or more was 3.1, P=0.0001. The combined mortality/heart failure hospitalisation incidence was 43.8% in the lowest and 14.6% in the combined upper three quartiles: Risk ratio 3.0, P<0.0001. In multivariate analysis, including age and history of atrial fibrillation, left atrioventricular plane displacement was an independent prognostic marker.

Conclusion: In post-myocardial infarction patients, echocardiographic assessment of atrioventricular plane displacement showed a strong, independent prognostic value. Determination of left atrioventricular plane displacement can be readily performed in virtually all patients, and may in clinical practice facilitate identification of high-risk patients.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0167-5273(02)00007-4DOI Listing

Publication Analysis

Top Keywords

atrioventricular plane
16
plane displacement
16
left atrioventricular
12
prognostication risk
8
risk stratification
8
myocardial infarction
8
acute myocardial
8
displacement assessed
8
patients
6
stratification assessment
4

Similar Publications

Background: Right ventricular (RV) function assessment by echocardiography can be challenging due to its complex morphology. Also, increasing use of sedation rather than general anesthesia for transfemoral approach transcatheter aortic valve replacement (TAVR) reduces the need for intraoperative transesophageal echocardiography (TEE). Recent clinical studies have demonstrated the importance of 3-dimensional (3D) echocardiography and a longitudinal strain for RV function assessment.

View Article and Find Full Text PDF
Article Synopsis
  • Mitral regurgitation (MR) is commonly found in patients with non-valvular atrial fibrillation (NVAF) and can worsen the condition; this study examines the 3D anatomy of the mitral valve (MV) in different NVAF types to understand MR's mechanisms.
  • The study analyzed 82 patients with paroxysmal AF and 66 with persistent AF via real-time 3D echocardiography, comparing them to a control group of 30 patients, measuring various heart structures and functions.
  • Results showed that persistent AF patients had larger left atrial volumes and higher MR rates, with notable changes in mitral annular shape and size compared to the control group, indicating structural changes are
View Article and Find Full Text PDF
Article Synopsis
  • During systole, the left ventricle shortens, moving the aortic root and stretching the ascending aorta, which impacts heart function.
  • A study revealed that stiffening of the ascending aorta increases stress in the left ventricle and leads to decreased muscle strain, particularly in the septal area.
  • Overall, aortic stiffening negatively affects left ventricular function, but increasing myofiber contractility could help recover some lost stroke volume despite persistent reductions in specific muscle strains.
View Article and Find Full Text PDF

Evolutionary Aspects of Chamber Formation and Septation.

Adv Exp Med Biol

June 2024

Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, Amsterdam, The Netherlands.

The formed hearts of vertebrates are widely different in anatomy and performance, yet their embryonic hearts are surprisingly similar. Developmental and molecular biology are making great advances in reconciling these differences by revealing an evolutionarily conserved building plan to the vertebrate heart. This suggests that perspectives from evolution may improve our understanding of the formation of the human heart.

View Article and Find Full Text PDF

Hydraulic force aids diastolic filling of the left ventricle (LV) by facilitating basal movement of the atrioventricular plane. The short-axis atrioventricular area difference (AVAD) determines direction and magnitude of this force. Patients with atrial septal defect (ASD) have reduced LV filling due to the left-to-right shunt across the atrial septum and thus potentially altered hydraulic force.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!