Monte Carlo calculations and TLD measurements have been performed for the purpose of characterizing dosimetric properties of new commercially available brachytherapy sources. All sources tested consisted of a solid core, upon which a thin layer of 125I has been adsorbed, encased within a titanium housing. The PharmaSeed BT-125 source manufactured by Syncor is available in silver or palladium core configurations while the ADVANTAGE source from IsoAid has silver only. Dosimetric properties, including the dose rate constant, radial dose function, and anisotropy characteristics were determined according to the TG-43 protocol. Additionally, the geometry function was calculated exactly using Monte Carlo and compared with both the point and line source approximations. The 1999 NIST standard was followed in determining air kerma strength. Dose rate constants were calculated to be 0.955+/-0.005, 0.967+/-0.005, and 0.962+/-0.005 cGy h(-1) x U(-1) for the PharmaSeed BT-125-1, BT-125-2, and ADVANTAGE sources, respectively. TLD measurements were in excellent agreement with Monte Carlo calculations. Radial dose function, g(r), calculated to a distance of 10 cm, and anisotropy function, F(r,theta), calculated for radii from 0.5 to 7.0 cm, were similar among all source configurations. Anisotropy constants, phi(an), were calculated to be 0.941, 0.944, and 0.960 for the three sources, respectively. All dosimetric parameters were found to be in close agreement with previously published data for similar source configurations. The MCNP Monte Carlo code appears to be ideally suited to low energy dosimetry applications.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724609 | PMC |
| http://dx.doi.org/10.1120/jacmp.v3i2.2576 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A library of proton lineal energy spectra spanning the full range of clinically relevant energies.
Med Phys
January 2025
Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, USA.
Purpose: In locations where the proton energy spectrum is broad, lineal energy spectrum-based proton biological effects models may be more accurate than dose-averaged linear energy transfer (LET) based models. However, the development of microdosimetric spectrum-based biological effects models is hampered by the extreme computational difficulty of calculating microdosimetric spectra. Given a precomputed library of lineal energy spectra for monoenergetic protons, a weighted summation can be performed which yields the lineal energy spectrum of an arbitrary polyenergetic beam.
View Article and Find Full Text PDFBackground And Purpose: Radiation induced image changes (IC) on MRI have been observed after proton therapy for brain tumours. This study aims to create predictive models, with and without taking into account patient variation, based on dose, linear energy transfer (LET) and periventricular zone (PVZ) in a national cohort of patients with glioma treated with pencil beam scanning (PBS).
Materials And Methods: A cohort of 87 consecutive patients with oligodendroglioma or astrocytoma (WHO grade 2-4) treated with PBS from January 2019 to December 2021 was included.
AI-enhanced X-ray spectrum reconstruction for medical imaging system.
Appl Radiat Isot
January 2025
School of Artificial Intelligence, Wenzhou Polytechnic, Wenzhou, 325035, China. Electronic address:
For the purpose of assessing image quality and calculating patient X-ray dosage in radiology, computed tomography (CT), fluoroscopy, mammography, and other fields, it is necessary to have prior knowledge of the X-ray energy spectrum. The main components of an X-ray tube are an electron filament, also known as the cathode, and an anode, which is often made of tungsten or rubidium and angled at a certain angle. At the point where the electrons generated by the cathode and the anode make contact, a spectrum of X-rays with energies spanning from zero to the maximum energy value of the released electrons is created.
View Article and Find Full Text PDFCounting efficiencies of shadow shield whole body counter for adult and paediatric reference computational phantoms.
Appl Radiat Isot
January 2025
Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, 400085, India.
Shadow Shield Whole Body Counter (SSWBC) is used to estimate internal dose of radiation workers due to the intake of fission and activation products. The SSWBC geometry was numerically modelled in FLUKA code. The computational model was validated by comparing the experimental and simulated counting efficiencies (CEs), also known as response, using Bhabha Atomic Research Centre (BARC) reference BOttle Mannequin Absorption (BOMAB) phantom.
View Article and Find Full Text PDFThe potential of the i-TED Compton camera array for real-time boron imaging and determination during treatments in Boron Neutron Capture Therapy.
Appl Radiat Isot
December 2024
Instituto de Física Corpuscular (CSIC-Universidad de Valencia), Valencia, Spain.
This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!