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Alopecia Induced by Poly-L-Lactic Acid Injection.
Cutis
November 2024
Drs. Cortez, Hassun, Linhares, Pinheiro, Florenço, Michalany, Bagatin, and Nascimento are from the Federal University of São Paulo, Brazil. Drs. Cortez, Hassun, Linhares, Pinheiro, Florenço, Bagatin, and Nascimento are from the Department of Dermatology, and Dr. Michalany is from the Department of Dermatopathology. Drs. Cortez de Almeida and Melo are from Department of Dermatology, Rio de Janeiro State University, Brazil.
Cosmetic procedures carry inherent risks of adverse events. Though rarely reported, transient and permanent alopecia are potential complications of these procedures. We report the case of a 35-year-old woman who developed pain and patches of nonscarring alopecia with erythema and edema following aesthetic application of poly-L-lactic acid (PLLA) on the face and along the frontal hairline.
View Article and Find Full Text PDFDetection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering.
BMC Cancer
January 2025
Nanfang Hospital, Southern Medical University, Guangzhou, China.
Background: To detect the differences in physical symptoms between depressed and undepressed patients with breast cancer (BC), including common symptoms, co-occurring symptoms, and symptom clusters based on texts derived from social media and expressive writing.
Methods: A total of 1830 texts from social media and expressive writing were collected. The Chi-square test was used to compare the frequency of physical symptoms between depressed and undepressed patients with BC.
Association Between Treatment-Related Adverse Event Trajectory and Prognosis in Esophageal Cancer Receiving Neoadjuvant Immunochemotherapy.
Ann Surg Oncol
December 2024
Department of Thoracic Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Background: Immunochemotherapy is inevitably accompanied with treatment-related adverse events (TRAEs). However, TRAEs are typically assessed at a single time point, overlooking the complexity of TRAE trajectories over time. This study aimed to characterize TRAE trajectories during multi-cycle neoadjuvant immunochemotherapy (nICT) and identify potential prognostic factors for patients with esophageal squamous cell carcinoma (ESCC).
View Article and Find Full Text PDFComparing the efficacy of oral apremilast, intralesional corticosteroids, and their combination in patients with patchy alopecia areata: a randomized clinical controlled trial.
Arch Dermatol Res
December 2024
Department of Dermatology, Venereology and Leprology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India.
Introduction: Alopecia areata (AA) is a chronic, immune-mediated inflammatory disorder characterized by nonscarring hair loss. The management of AA poses challenges due to its unpredictable course and variable response to treatment. In this comparative study, we evaluated the efficacy and safety of oral apremilast, intralesional corticosteroids (ILC) and a combination of both in patients with patchy AA.
View Article and Find Full Text PDFArticle Synopsis
- * The review analyzed 286 articles, ultimately including 11 studies with over 19,000 patients; it found injectable minoxidil significantly improved hair growth for androgenetic alopecia, while results for alopecia areata varied.
- * Overall, injectable minoxidil appears to be a safe and effective treatment for androgenetic alopecia, with further research needed to determine optimal dosing and understand its effects on alopecia areata.
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