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Mal de Debarquement (MdD) is a rare vestibular disorder characterized by a rocking or swaying sensation following passive motion exposure, such as boat or airplane travel. The etiology and pathogenesis are unknown. Due to a lack of clinical awareness and research, it is underrecognized and misdiagnosed.

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Mal de debarquement syndrome (MdDS), also known as "the sickness of disembarkment," is characterized by a persistent bobbing, rocking, or swaying sensation reported by patients long after they have completed travel on a boat or other forms of extended transportation. A detailed patient history, focusing on specific inquiries about recent boat or ship travel, is crucial for a timely diagnosis. The syndrome is unique in that reintroducing similar movements, such as driving, swinging, or returning to the boat, alleviates symptoms temporarily.

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Virtual reality application matches the most established treatment for Mal de Debarquement Syndrome: A non-inferiority, randomized, open clinical trial.

Neurotherapeutics

September 2024

Lab for Equilibrium Investigations and Aerospace, University of Antwerp, Antwerp, Belgium; Telmio BV, Luchthavenlaan 27, Vilvoorde, Belgium; European Institute for ORL-HNS, Sint-Augustinus Hospital, Wilrijk, Belgium.

Mal de Debarquement Syndrome (MdDS) is a debilitating neuro-otological disorder where individuals consistently feel self-motion, often triggered by motion like being on a boat (MT-MdDS). Due to the unknown pathophysiological mechanism, available treatment options for managing symptoms are limited. Our objective was to develop a virtual reality application (VRA) to simulate the full field optokinetic stimulation (OKS) booth and evaluate its efficacy compared to the standard treatment.

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