Recombinant protein expression for therapeutic applications.

Curr Opin Biotechnol

Cell Culture & Fermentation Research & Development, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Published: April 2002

In recent years, the number of recombinant proteins used for therapeutic applications has increased dramatically. Many of these applications involve complex glycoproteins and antibodies with relatively high production needs. These demands have driven the development of a variety of improvements in protein expression technology, particularly involving mammalian and microbial culture systems.

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http://dx.doi.org/10.1016/s0958-1669(02)00300-2DOI Listing

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