Oligonucleotide- and cDNA-based microarrays comprising a subset of Neisseria meningitidis genes were assessed for study of the meningococcal heat shock response and found to be highly suitable for transcriptional profiling of N. meningitidis. Employing oligonucleotide arrays encompassing the entire genome of N. meningitidis, we analyzed the meningococcal heat shock response on a global scale and identified 55 heat shock-deregulated open reading frames (34 induced and 21 repressed).
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134990 | PMC |
| http://dx.doi.org/10.1128/JB.184.9.2546-2551.2002 | DOI Listing |
Publication Analysis
Top Keywords
heat shock
12
shock response
12
neisseria meningitidis
8
meningococcal heat
8
analysis heat
4
response neisseria
4
meningitidis
4
meningitidis cdna-
4
cdna- oligonucleotide-based
4
oligonucleotide-based dna
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!