Power analysis can be a valuable aid in the design of monitoring programs. It requires an estimate of variance, which may come from a pilot study or an existing study in a similar habitat. For marine benthic infauna, natural variation in abundances can be considerable, raising the question of reliability of variance estimates. We used two existing monitoring programs to generate multiple estimates of variance. These estimates were found to differ from nominated best estimates by 50% or more in 43% of cases, in turn leading to under or over-estimation of sample size in the design of a notional monitoring program. The two studies, from the same general area, using the same sampling methods and spanning a similar time scale, gave estimates varying by more than an order of magnitude for 25% of taxa. We suggest that pilot studies for ecological monitoring programs of marine infauna should include at least two sampling times.
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http://dx.doi.org/10.1023/a:1014280405278 | DOI Listing |
Introduction: This study aimed to identify cognitive tests that optimally relate to tau positron emission tomography (PET) signal in the inferior temporal cortex (ITC), a neocortical region associated with early tau accumulation in Alzheimer's disease (AD).
Methods: We analyzed cross-sectional data from the harvard aging brain study (HABS) (= 128) and the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study (= 393). We used elastic net regression to identify the most robust cognitive correlates of tau PET signal in the ITC.
ERJ Open Res
January 2025
Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, Division of Cardiology, Department of Medicine, University of Pittsburgh School of Medicine and UPMC, Pittsburgh, PA, USA.
Background: Pulmonary arterial hypertension (PAH) is a deadly disease without effective non-invasive diagnostic and prognostic testing. It remains unclear whether vasodilators reverse inflammatory activation, a part of PAH pathogenesis. Single-cell profiling of inflammatory cells in blood could clarify these PAH mechanisms.
View Article and Find Full Text PDFERJ Open Res
January 2025
Department of Otolaryngology-Head and Neck Surgery, University of California, Los Angeles, Los Angeles, CA, USA.
Background: Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are prevalent disease complications in people with cystic fibrosis. These understudied comorbidities significantly impact quality of life. The impact of highly effective modulator therapy (HEMT) in young children with cystic fibrosis (YCwCF) on these disease complications is unknown.
View Article and Find Full Text PDFData Brief
February 2025
Woodwell Climate Research Center, 149 Woods Hole Rd., Falmouth, MA, 02540, United States.
This near-infrared spectral dataset consists of 2,106 diverse mineral soil samples scanned, on average, on six different units of the same low-cost commercially available handheld spectrophotometer. Most soil samples were selected from the USDA NRCS National Soil Survey Center-Kellogg Soil Survey Laboratory (NSSC-KSSL) soil archives to represent the diversity of mineral soils (0-30 cm) found in the United States, while 90 samples were selected from Ghana, Kenya, and Nigeria to represent available African soils in the same archive. All scanning was performed on dried and sieved (<2 mm) soil samples.
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