Fidelity scales have become an accepted part of intervention research. Initially, fidelity scales focused on critical components of an intervention. In this paper we argue that the next generation of fidelity scales should include key process variables such as choice. Since choice is an essential element in all empowerment and recovery driven intervention models, a fidelity scale for an enhanced version of the Individual Placement and Support (IPS) supported employment model that incorporates choice as a fundamental component was developed as part of a SAMHSA community action grant. The process for developing the choice component and the dimensions measured are also described.
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http://dx.doi.org/10.1023/a:1014591020400 | DOI Listing |
3D Print Med
January 2025
Department of Surgical & Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Background: Penile implant surgery is the standard surgical treatment for end-stage erectile dysfunction. However, the growing complexity of modern high-tech penile prostheses has increased the demand for more practical training opportunities. The most advanced contemporary training methods involve simulation training using cadavers, with costs exceeding $5,000 per cadaver, inclusive of biohazard fees.
View Article and Find Full Text PDFProteins have proven to be useful agents in a variety of fields, from serving as potent therapeutics to enabling complex catalysis for chemical manufacture. However, they remain difficult to design and are instead typically selected for using extensive screens or directed evolution. Recent developments in protein large language models have enabled fast generation of diverse protein sequences in unexplored regions of protein space predicted to fold into varied structures, bind relevant targets, and catalyze novel reactions.
View Article and Find Full Text PDFEur J Pediatr
January 2025
Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
Unlabelled: Effective leadership is essential in neonatal intensive care units (NICUs), where complex, high-stakes environments require coordinated multidisciplinary teamwork. Strong leadership improves clinical outcomes, team performance, and staff well-being. This systematic review assesses various leadership models and interventions in NICUs to identify best practices and areas for future research.
View Article and Find Full Text PDFInt J Pharm
January 2025
SSPC Research Centre, Department of Chemical Sciences & Chemical Engineering, Bernal Institute, University of Limerick, Limerick V94 T9PX Ireland. Electronic address:
Atomization-based techniques are widely used in pharmaceutical industry for production of fine drug particles due to their versatility and adaptability. Key performance measure of such techniques is their ability to provide control over critical quality attributes (CQAs) of produced drug particles. CQAs of drug particles produced via atomization critically depend on fluid dynamics of sprays; resulting mixing, heat and mass transfer; distribution of supersaturation and subsequent nucleation and growth of particles.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.
Objective: To validate the use of neural radiance fields (NeRF), a state-of-the-art computer vision technique, for rapid, high-fidelity 3-dimensional (3D) reconstruction in endoscopic sinus surgery (ESS).
Study Design: An experimental cadaveric pilot study.
Setting: Academic medical center.
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