Oral ulcerations have very varied characteristics, the analysis of which is often sufficient for the clinician to establish a diagnosis and propose a suitable treatment. Aphthous ulcers and traumatic lesions are the most frequent, however one also sees infectious ulcerations (tuberculous, syphilitic, common germs or viruses), inflammatory diseases of the gastrointestinal tract, bullous dermatosis of autoimmune, toxic or unknown origin such as erythema multiform, and erosive lichen planus. It is thus the general context or the evolution that orientates the diagnosis, which is made more precise in certain cases by complementary investigations, in particular by the biopsy. When the ulceration is isolated it is necessary to first exclude the much-feared squamous cell carcinoma, but also other malignant ulcerated tumours, lymphomas, and tumours of the salivary glands. Thus it is imperative that the histological examination confirms the diagnosis, to formulate a prognosis and to allow the commencement of treatment.
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Microbiol Spectr
January 2025
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
is a vector of several human pathogens in the United States, including the cause of Lyme disease, and Powassan virus (POWV), an emerging cause of severe encephalitis. Skin biopsies from tick bite sites are frequently collected and tested for the presence of spirochetes ( spp.), which remain elusive.
View Article and Find Full Text PDFJ Contemp Dent Pract
September 2024
Department of Conservative Dentistry and Endodontics, PMNM Dental College and Hospital, Bagalkot, Karnataka, India.
Aim: The present study is aimed to compare the effectiveness of dentinal tubule occlusion of two natural-based desensitizing toothpaste (Bentodent Desensitizer and Fang Farm Mint) and Novamin-based toothpaste (Shy-NM) under scanning electron microscope (SEM).
Materials And Methods: A total of 60 root dentin discs (3 mm-thick) were obtained from recently extracted permanent premolar teeth and were randomly divided into four groups based on the desensitizing toothpaste used, each group with 15 samples: Group I: Control, group II: Shy-NM, group III: Bentodent desensitizer, group IV: Fang Farm Mint. Samples were brushed for 2 min twice daily with a soft toothbrush with respective pea size amount of toothpaste for 14 days manually.
Cureus
December 2024
Oral Pathology and Microbiology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Body piercing has become popular among people of all ages, inspired by religious convictions, personal aesthetics, and cultural influences. Piercings in the oral cavity frequently involve the lip, buccal mucosa, frenulum, and tongue with needles, hooks, and rings. However, these piercings might cause long-term problems to both the hard and soft tissues of the mouth.
View Article and Find Full Text PDFJ Family Med Prim Care
December 2024
Department of Microbiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India.
Background: Pulmonary tuberculosis (PTB) accounts for 85% of all reported tuberculosis cases globally. Extrapulmonary involvement can occur in isolation or along with a pulmonary focus as in the case of patients with disseminated tuberculosis (TB). EPTB can occur through hematogenous, lymphatic, or localized bacillary dissemination from a primary source, such as PTB and affects the brain, eye, mouth, tongue, lymph nodes of neck, spine, bones, muscles, skin, pleura, pericardium, gastrointestinal, peritoneum and the genitourinary system as primary and/or disseminated disease.
View Article and Find Full Text PDFSci Rep
January 2025
Office of Research Affairs, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Although the modulus of elasticity of the human periodontal ligament (E) values used in dentistry widely ranged from 0.01 to 175 MPa, the exact E value has not been determined. This study aimed to verify whether and how E values affect the stress distribution over the tooth and periodontium structures, and to determine the appropriate E range.
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