[Primary clinical study on self-setting calcium phosphate cement in bone defect repair of extremities].

Objective: To investigate the clinical application of self-setting calcium phosphate cement (CPC) in bone defect repair of extremities.

Methods: From May 1998 to January 2000, 32 cases of bone defect, in 36 sites, were repaired and reviewed, aged from 4 to 59 years old (24.7 years old on average), with bone defect 2 to 125 cm2 in size (13.1 cm2 on average). The causes of the bone defect were fracture, bone cyst, iliac bone harvesting, fibrous dysplasia, enchondroma and bone tuberculosis, which involved femur, iliac, tibia, humerus, phalanx, fibula, calcaneus, talus and acetabulum. All of the cases were followed up for 1 to 23 months, 15.3 months on average, before radiographic examination.

Results: All operations were successful and no general response was observed in all of the cases. X-ray examination showed an integrity interface between CPC and bone. And CT showed no gap existed. There was no increase of serum calcium and phosphate levels.

Conclusion: CPC is applicable in the low- or non-weight-bearing site of the extremities.