Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
This study was undertaken to examine the effect of stimulus energy on electroconvulsive therapy (ECT)-induced prolactin (PRL) release. Patients undergoing a course of right unilateral or bilateral ECT were studied during two consecutive treatments. The order of high- and low-energy ECT was counterbalanced between the two treatments. A multivariate repeated-measures analysis of variance with seizure duration within each condition (high/low energy ECT) used as a covariate showed that seizure duration was not significantly different between conditions, but was significantly related to PRL release. However, PRL increase in response to high-energy ECT was significantly higher compared with low-energy ECT. These results indicate that in addition to the previously demonstrated relationship between electrode placement and ECT-induced PRL response, PRL release also varies as a function of stimulus energy. The implications of the hypothesis that this neuroendocrine response could serve as an indication that an effective stimulus has been delivered are discussed.
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