AI Article Synopsis
- The School of Public Health and Tropical Medicine at James Cook University conducted filariasis surveys in Papua New Guinea from 1991 to 1997.
- The surveys utilized new diagnostic methods, including the Onchocerca gibsoni monoclonal assay and immunochromatographic tests, alongside the Knott's test for microfilariae.
- Findings showed a high prevalence of filarial antigenaemia (56%) and microfilaraemia (35%), with antigen tests identifying 25% more cases than Knott's, highlighting their effectiveness and quick results for public health surveys.
Article Abstract
During the period from 1991 to 1997 the School of Public Health and Tropical Medicine, James Cook University carried out filariasis surveys in several parts of Papua New Guinea using the newly introduced Onchocerca gibsoni monoclonal (Og4C3) and immunochromatographic test (ICT) antibody-based assays for filarial antigen and, in some cases, a Knott's test for microfilariae. The average prevalence of filarial antigenaemia and microfilaraemia was 56% and 35% respectively confirming earlier survey results that filariasis is hyperendemic in many parts of the country. The antigen tests detected 25% more cases than the Knott's test and the simplicity of the ICT and its capacity to produce almost instant results make it an ideal tool for surveys.
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