Objective: To determine the percentage occurrence, demographic and clinical features of psoriasis in adult patients at King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia.
Methods: The medical records of all the adult patients with psoriasis were analyzed from January 1991 to December 1994 at the dermatology clinic, King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia.
Results: A total of 263 adult psoriatic patients were studied with the percentage occurrence of 5.3%. There was a male preponderance with sex ratio of 1.4:1. The mean age of onset in males was 26.9 years while in females it was 22.3 years. Fifty-three percent of psoriatic cases developed before the age of 30 years. Family history of psoriasis was recorded in 8.4% of the cases. Itching was the only symptom reported by patients in 43% of cases. The sites of involvement were as follows: lower extremity 44.9%, scalp 41.8%, nail 26.6% and palmoplanter 12.6%. Plaque psoriasis was the most common clinical type (87.1%), followed by erythrodermic (4.2%), pustular (3%), guttate (1.9%), flexural, (2.3%) and follicular (0.4%).
Conclusion: The present study represents the apparent magnitude of psoriasis in the eastern province of Saudi Arabia, which may reflect that the disease is common in our area as elsewhere. The clinical features of psoriasis in our patients were similar to those reported from other parts of the world.
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S D Med
December 2024
Department of Internal Medicine, University of South Dakota Sanford School of Medicine.
Background: Francisella tularensis is an aerobic, gram negative coccobacillus bacterium that causes tularemia. F. tularensis spreads primarily through ticks, biting flies, droplet inhalation, contaminated mud or water, or infected animal bites, and it can survive in animal carcasses with the most common mode of transmission occurring via inoculation into the skin and inhalation/ingestion.
View Article and Find Full Text PDFAcad Pathol
December 2024
Department of Pathology & Anatomy, Eastern Virginia Medical School, Norfolk, VA, USA.
J Am Acad Dermatol
December 2024
Department of Dermatology, Larkin Community Hospital Palm Springs Campus Dermatology Resident Program, Hialeah, Florida.
Background: Psoriasis is a chronic inflammatory skin disease often associated with obesity. Psoriasis therapies may be less effective in patients with obese. The purpose of this expert consensus panel is to evaluate the relationship between obesity and efficacy of psoriasis therapies, thereby optimizing patient care.
View Article and Find Full Text PDFJAMA Dermatol
December 2024
Innovative Dermatology, Plano, Texas.
Importance: Diverse racial and ethnic representation in clinical trials has been limited, not representative of the US population, and the subject of pending US Food and Drug Administration guidance. Psoriasis presentation and disease burden can vary by skin pigmentation, race and ethnicity, and socioeconomic differences. Overall, there are limited primary data on clinical response, genetics, and quality of life in populations with psoriasis and skin of color (SoC).
View Article and Find Full Text PDFJ Dermatolog Treat
December 2024
Samsung Bioepis, Co. Ltd, Incheon, South Korea.
Introduction: SB17 is a biosimilar to reference ustekinumab (UST). We compared the efficacy, safety, and immunogenicity of SB17 to UST up to Week 52, including switching from UST to SB17.
Methods: Subjects were randomized to receive 45 mg of SB17 or UST subcutaneously up to Week 40.
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