Study Design: A prospective cohort study of workers with low back pain who had been absent from work for more than 4 weeks was conducted.
Objective: To assess the discriminative and predictive validity of the Quebec Task Force Classification for workers during the subacute phase of disability from back pain.
Summary Of Background Data: The Quebec Task Force Classification was designed for clinical decision making, prognosis establishment, quality of care evaluation, and scientific research in low back pain.
Methods: For this study, 104 workers absent from work because of back pain were classified according to the first four categories of the Quebec Task Force Classification 4 weeks after their first day of work absence. They then were randomized into four treatment groups: standard care (control), clinical-rehabilitation intervention, occupational intervention, and the Sherbrooke model (a combination of the clinical-rehabilitation and occupational interventions). Functional status, pain level, and work status were assessed at baseline and after 1 year. Duration of full compensation and back-related costs were calculated over a mean follow-up period of 6.5 years. The discriminative validity of the Quebec Task Force Classification was evaluated using Kendall tau correlation coefficients. Predictive validity was evaluated using logistic regression analyses. Age, gender, comorbidities, body mass index, and treatment group were considered as potential confounders.
Results: Significant but low correlation coefficients were found between Quebec Task Force Classification categories and functional status scores at baseline. Subjects classified as having distal radiating pain (categories 3 and 4) at baseline were more likely to have a lower functional status, higher pain level, and no return to regular work at the 1-year follow-up evaluation. They also were more likely to accumulate more days of full compensation and to cost more after a mean follow-up period of 6.5 years.
Conclusion: The Quebec Task Force Classification demonstrated good predictive ability by discriminating between subjects with and those without distal radiating pain.
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http://dx.doi.org/10.1097/00007632-200204150-00013 | DOI Listing |
J Biomed Phys Eng
December 2024
Department of Medical Physics & Biomedical Eng., School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Background: Acquiring new knowledge necessitates alterations at the synaptic level within the brain. Glutamate, a pivotal neurotransmitter, plays a critical role in these processes, particularly in learning and memory formation. Although previous research has explored glutamate's involvement in cognitive functions, a comprehensive understanding of its real-time dynamics remains elusive during memory tasks.
View Article and Find Full Text PDFNeuroimage
December 2024
INSERM U1114, Cognitive Neuropsychology and Pathophysiology of Schizophrenia, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France; INSERM U1329, team Psychiatry of STEP (Strasbourg Translational nEuroscience and Psychiatry), 1 place de l'Hôpital, 67091 Strasbourg Cedex, France. Electronic address:
Time prediction is pervasive, and it is unclear whether it is supra-modal or task-specific. This study aimed to investigate the role of motor temporal prediction in preparing to stop a movement following a sensory stimulus. Participants performed a straight-line movement with their finger until a target signal, which occurred after a short or long foreperiod.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Mila - Quebec Artificial Intelligence Institute, Montréal, Canada.
Neurons in the brain have rich and adaptive input-output properties. Features such as heterogeneous f-I curves and spike frequency adaptation are known to place single neurons in optimal coding regimes when facing changing stimuli. Yet, it is still unclear how brain circuits exploit single-neuron flexibility, and how network-level requirements may have shaped such cellular function.
View Article and Find Full Text PDFUltramicroscopy
December 2024
Department of Mining and Materials Engineering, McGill University, Montreal, Quebec, Canada.
Acquiring multiple high magnification, high resolution images with scanning electron microscopes (SEMs) for quantitative analysis is a time consuming and repetitive task for microscopists. We propose a workflow to automate SEM image acquisition and demonstrate its use in the context of nanoparticle (NP) analysis. Acquiring multiple images of this type of specimen is necessary to obtain a complete and proper characterization of the NP population and obtain statistically representative results.
View Article and Find Full Text PDFLancet Reg Health Am
December 2024
Vaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Background: The Canadian National Vaccine Safety Network conducted active safety surveillance for COVID-19 vaccines. This study aimed to characterize the short-to-medium term safety of mRNA COVID-19 vaccines across the pediatric age spectrum.
Methods: In this cohort study, vaccinated and unvaccinated children and adolescents aged 6 months to 19 years from eight Canadian provinces and territories were invited to participate.
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