A series of novel phosphonoboronates consisting of PC(1)B, PC(n)B, PC(X)C(n)B, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.
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| http://dx.doi.org/10.1016/s0960-894x(02)00110-5 | DOI Listing |
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