The article concentrates on the process of diagnosing disease, especially of common health problems. The biomedical concept dominates medicine in our days. However, the majority of the complaints presented to the general practician cannot be classified as distinct disease entities. An integral concept is far more suitable to integrate biomedical and psychosocial factors. In this way biomedical aspects acquire significance within an individual life story and social context in which gender plays a role. That is why the integral concept is more adequate to focus on sex differences in the diagnostic process. The article describes the impediments in this process, mainly due to the fact the prevailing concepts of disease ignore sex differences.
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JMIR Form Res
January 2025
Early Intervention in Psychosis Advisory Unit for South-East Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Background: Shared decision-making between clinicians and service users is crucial in mental health care. One significant barrier to achieving this goal is the lack of user-centered services. Integrating digital tools into mental health services holds promise for addressing some of these challenges.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
Faculty of Health, Nursing, Management, University of Applied Sciences Neubrandenburg, Neubrandenburg, Germany.
Background: In Germany, digital transformation and legal regulations are leading to the need to integrate digital technologies into the nursing profession. In addition, to nursing practice, they are also being incorporated into nursing training. Despite comprehensive regulations regarding the use of digital teaching and learning media in nursing education, their specific applicability and implementation vary.
View Article and Find Full Text PDFPLOS Glob Public Health
January 2025
Institute of Anatomy, Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Peru is among Latin American countries with the largest Indigenous population, yet ethnical health disparities persist, particularly in the Amazon region which comprises 60% of the national territory. Healthcare models that include Indigenous medicine and traditional healers present an important avenue for addressing such inequalities, as they increase cultural adequacy of services, healthcare access, and acknowledge Indigenous Rights for their perspectives to be represented in public healthcare. Understanding the underlying epistemologies of Indigenous medicine is a prerequisite for this purpose.
View Article and Find Full Text PDFBackground: The Professional Identity in Nursing Initiative began in 2018 to explore how concepts and language regarding professional identity formation could positively affect nursing education, practice, and regulation. In 2023, faculty from two nursing schools used the International Society for Professional Identity in Nursing (ISPIN) definitions and domains to incorporate professional identity in nursing language in a template for a nursing student handbook.
Method: Faculty evaluated the professional identity in nursing model and replaced the framework for professionalism in the school of nursing's handbook.
J Chem Inf Model
January 2025
Department of Life Science Informatics and Data Science, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, Bonn D-53115, Germany.
Explaining the predictions of machine learning models is of critical importance for integrating predictive modeling in drug discovery projects. We have generated a test system for predicting isoform selectivity of phosphoinositide 3-kinase (PI3K) inhibitors and systematically analyzed correct predictions of selective inhibitors using a new methodology termed MolAnchor, which is based on the "anchors" concept from explainable artificial intelligence. The approach is designed to generate chemically intuitive explanations of compound predictions.
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