Objective: To compare three implant systems in patients with severely resorbed mandibles 1 year after insertion of the mandibular denture.
Design: A prospective multicenter randomized clinical trial.
Setting: Centers at University of Nijmegen and Groningen.
Methods: Three different implant systems were used: the transmandibular implant, the IMZ and the Brånemark system. Treatment was assigned to 88 patients according to a balanced allocation method. Evaluation included clinical and radiographic parameters. A Clinical Implant Performance scale (CIP) was constructed based on all conceivable complications of the different implant systems.
Results: During the healing period 1 IMZ- and 1 BRA-implant were lost. One TMI was removed after functional loading. The results of the clinical and radiographic parameters and the CIP-scale showed no significant differences between the three implant systems.
Conclusion: Taking the one year evaluation into account the three systems used did not differ in clinical and radiographic performance.
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Langenbecks Arch Surg
January 2025
Department of Trauma Surgery, University Hospital Zurich, Rämistrasse 100, CH - 8091, Zurich, Switzerland.
Introduction: Blunt traumatic aortic injury (TAI) is a critical condition and a leading cause of mortality in trauma patients, often resulting from high-speed accidents. Thoracic endovascular aortic repair (TEVAR) has developed into the preferred therapeutic approach due to its minimally invasive nature and promising outcomes. This study evaluates the safety and efficacy of TEVAR for managing TAI over a 10-year period at a Level-1 trauma center.
View Article and Find Full Text PDFXenotransplantation
January 2025
Beijing Key Laboratory of Preclinical Research and Evaluation for Cardiovascular Implant Materials, Animal Experimental Centre, National Centre for Cardiovascular Disease, Department of Cardiac Surgery, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Organ transplants are used to treat many end-stage diseases, but a shortage of donors means many patients cannot be treated. Xenogeneic organs have become an important part of filling the donor gap. Many current studies of kidney, heart, and liver xenotransplantation have used gene-edited pig organs on brain-dead recipients.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Sports Medicine & Orthopedic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China.
Clin Breast Cancer
December 2024
Department of General Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Shilin, Taipei, Taiwan; Breast Cancer Center, Shin Kong Wu Ho-Su Memorial Hospital, Shilin, Taipei, Taiwan; School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan; School of Medicine, College of Medicine, Fu Jen Catholic University, Taipei, Taiwan. Electronic address:
Background: The use of robotic-assisted nipple-sparing mastectomy (R-NSM) with immediate direct-to-implant (DTI) reconstruction in treatment of breast cancer has been a controversial topic. The adoption of robotic surgery in breast cancer treatment has gained traction globally due to its minimally invasive nature, potential for improved cosmetic outcomes and better intraoperative visualization. This study provides insights on safety and feasibility robotic mastectomy at one of the largest centers in Asia.
View Article and Find Full Text PDFActa Biomater
January 2025
Central laboratory of Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China. Electronic address:
Peripheral nerve injury (PNI) as a common clinical issue that presents significant challenges for repair. Factors such as donor site morbidity from autologous transplantation, slow recovery of long-distance nerve damage, and deficiencies in local cytokines and extracellular matrix contribute to the complexity of effective PNI treatment. It is extremely urgent to develop functional nerve guidance conduits (NGCs) as substitutes for nerve autografts.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!