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Prevalence, molecular characterization, antibiotic resistance, and investigation of transmission pathways of Listeria monocytogenes strains isolated along the beef production chain.
Food Microbiol
August 2025
Laboratory of Animal Food Products Hygiene-Veterinary Public Health, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece. Electronic address:
Listeria monocytogenes, the leading cause of fatalities among foodborne pathogens, exhibits remarkable resilience in food industry environments. This study aims to isolate and characterize L. monocytogenes strains along the beef production chain of a vertically integrated industry.
View Article and Find Full Text PDFImpact of tebipenem pivoxil on the intestinal microbiota and on establishment of colonization with carbapenem-resistant in mice.
Microbiol Spectr
March 2025
Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Tebipenem pivoxil has potent activity against pathogens, but requires combination with β-lactamase inhibitor to achieve activity against carbapenemase producers, including metallo-β-lactamases (MBLs). Herein, we evaluate the potential of tebipenem pivoxil, alone and in combination with the prodrug of the experimental MBL inhibitor CS319 (CS319-piv-SAc), to disrupt the indigenous mice microbiota of the colon and promote colonization by pathogens. The effect of antibiotic treatment (daily for 3 days with subcutaneous saline [control], subcutaneous clindamycin, oral tebipenem pivoxil alone and in combination with CS319-piv-Sac, or oral CS319-piv-Sac) on the intestinal microbiota was assessed by culture for enterococci and facultative Gram-negative bacilli and by 16S rRNA amplicon sequencing.
View Article and Find Full Text PDFRe-challenging pralsetinib following recovery from pneumocystis jirovecii pneumonia in a lung cancer patient: a Case Report.
Front Pharmacol
February 2025
Department of Oncology, Jinan Central Hospital, Shandong University, Jinan, Shandong, China.
Background: Pneumocystis jirovecii pneumonia (PJP), an opportunistic infection, is commonly observed in immunocompromised individuals, particularly those with cancer, and is known for its significant morbidity and mortality rates. Pralsetinib is a highly specific inhibitor that targets advanced or metastatic non-small cell lung cancer (NSCLC) characterized by RET-fusion positivity. The incidence of PJP infection in patients receiving pralsetinib was found to be infrequent.
View Article and Find Full Text PDFMusculoskeletal infections caused by streptococcus infantarius - a case series and review of literature.
Int Orthop
March 2025
University Hospital of Bonn, Department of Orthopedics and Trauma Surgery, Bonn, Germany.
Purpose: The full spectrum of diseases caused by S. infantarius remains poorly understood, particularly its role in musculoskeletal infections.
Methods: A retrospective study was conducted from January 2008 to May 2024.
Knowledge, attitude, and practices regarding methicillin-resistant Staphylococcus aureus (MRSA) infection control and nasal MRSA carriage rate among dental students of Al-Quds university, Palestine.
BMC Oral Health
March 2025
Department of Microbiology and Immunology, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Background: The nose is the primary colonization site of S. aureus which is a known risk factor for causing S. aureus infection.
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