Benign fibrous histiocytomas of the skin, or dermatofibromas, are common fibrohistiocytic tumors that affect women more commonly than men. Proposed causes range from a reactive process to a neoplastic growth. We report on a family affected with numerous dermatofibromas, suggesting that there also may be a genetic cause to this common tumor.
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Article Synopsis
- Multiple eruptive dermatofibroma (MEDF) is a rare skin condition often linked to diseases like HIV or lupus, characterized by specific skin histology.
- A case study reports a 30-year-old man with a 10-year history of numerous dark brownish-red spots on his skin, diagnosed with MEDF after ruling out infections and autoimmune diseases.
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Multiple dermatofibromas (DFs) are rare benign fibrohistiocytic lesions characterized by asymptomatic hyperpigmented nodules. Several diseases, like systemic lupus erythematosus (SLE) and human immunodeficiency virus (HIV) infection, are found to be associated with multiple DFs. Here, we designed a systematic review by an electronic search of PubMed and Embase databases to select case reports of multiple DFs (29 May 2021).
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