A 73-year-old woman with chronic renal failure developed generalized muscular weakness and pain 6 days after the start of allopurinol treatment(200 mg/day). Routine laboratory tests revealed elevated levels of serum creatine kinase, and the patient was clinically diagnosed as rhabdomyolysis, due probably to severe myositis. A high level of serum oxipurinol, the chief active metabolite of allopurinol, was also revealed. The muscular weakness was relieved in seven weeks with intermittent hemodiafiltration.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
chronic renal
8
renal failure
8
muscular weakness
8
case allopurinol-induced
4
allopurinol-induced muscular
4
muscular damage
4
damage chronic
4
failure patient]
4
patient] 73-year-old
4
73-year-old woman
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!