Objective: To evaluate the influence of lung volume on dependent lung opacity seen at thin-section CT.
Materials And Methods: In thirteen healthy volunteers, thin-section CT scans were performed at three levels (upper, mid, and lower portion of the lung) and at different lung volumes (10, 30, 50, and 100% vital capacity), using spirometric gated CT. Using a three-point scale, two radiologists determined whether dependent opacity was present, and estimated its degree. Regional lung attenuation at a level 2 cm above the diaphragm was determined using semiautomatic segmentation, and the diameter of a branch of the right lower posterior basal segmental artery was measured at each different vital capacity.
Results: At all three anatomic levels, dependent opacity occurred significantly more often at lower vital capacities (10, 30%) than at 100% vital capacity (p = 0.001). Visually estimated dependent opacity was significantly related to regional lung attenuation (p < 0.0001), which in dependent areas progressively increased as vital capacity decreased (p < 0.0001). The presence of dependent opacity and regional lung attenuation of a dependent area correlated significantly with increased diameter of a segmental arterial branch (r = 0.493 and p = 0.0002; r = 0.486 and p = 0.0003, respectively).
Conclusion: Visual estimation and CT measurements of dependent opacity obtained by semiautomatic segmentation are significantly influenced by lung volume and are related to vascular diameter.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713983 | PMC |
| http://dx.doi.org/10.3348/kjr.2002.3.1.24 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Histopathology of Abemaciclib-Induced Interstitial Lung Disease: A First Case Report With Transbronchial Lung Cryobiopsy.
Breast Cancer (Auckl)
November 2024
Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Abemaciclib, a cyclin-dependent kinase 4/6 inhibitor, is crucial in treating hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic or recurrent breast cancer. However, its association with drug-induced interstitial lung disease (DI-ILD) is concerning. We present an 82-year-old woman with breast cancer receiving abemaciclib, who developed persistent cough and malaise.
View Article and Find Full Text PDFZebrafish are resilient to the loss of major diacylglycerol acyltransferase enzymes.
J Biol Chem
November 2024
Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA; Department of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA. Electronic address:
In zebrafish, maternally deposited yolk is the source of nutrients for embryogenesis prior to digestive system maturation. Yolk nutrients are processed and secreted to the growing organism by an extra-embryonic tissue, the yolk syncytial layer (YSL). The export of lipids from the YSL occurs through the production of triacylglycerol-rich lipoproteins.
View Article and Find Full Text PDFCanonical ligand-dependent and non-canonical ligand-independent EphA2 signaling in the eye lens of wild-type, knockout, and aging mice.
Aging (Albany NY)
October 2024
School of Optometry and Vision Science Program, Indiana University, Bloomington, IN 47405, USA.
Disruption of Eph-ephrin bidirectional signaling leads to human congenital and age-related cataracts, but the mechanisms for these opacities in the eye lens remain unclear. Eph receptors bind to ephrin ligands on neighboring cells to induce canonical ligand-mediated signaling. The EphA2 receptor also signals non-canonically without ligand binding in cancerous cells, leading to epithelial-to-mesenchymal transition (EMT).
View Article and Find Full Text PDFAnalyzing the structural, optoelectronic, and thermoelectric properties of InGeX (X = Br) perovskites via DFT computations.
Sci Rep
October 2024
Condensed Matter Theory Group, School of Studies in Physics, Jiwaji University, Gwalior, 474011, India.
The Electronic and optical properties of InGeX(X = Cl, Br) were examined by adopting the density functional theory (DFT) approach. We applied the GGA + Trans-Blaha modified Becke-Johnson (TB-mBJ) technique to acquire the precise bandgap of 1.52 and 0.
View Article and Find Full Text PDFConcurrent perception of competing predictions: A "split-stimulus effect".
J Vis
October 2024
Melbourne School of Psychological Sciences, the University of Melbourne, Melbourne, Australia.
Article Synopsis
- Visual illusions are systematic misperceptions that reveal how our brains construct visual experiences, with the "frame effect" being a notable example where moving frames mislead our perception of an object's position.
- A newly identified illusion, the "split stimulus effect," shows that symmetrical motion of overlaid frames can cause observers to perceive two instances of a single stimulus, as evidenced by participants sometimes reporting two dots when only one was shown.
- This study also explored factors influencing the illusion, such as frame speed and spatial attention, and demonstrated that individuals can hold conflicting perceptual predictions about the same object, shedding light on the underlying mechanisms of visual perception.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!