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Schisandra sphenanthera extract modulates sweet taste receptor pathway, IRS/PI3K, AMPK/mTOR pathway and endogenous metabolites against T2DM.
Phytomedicine
January 2025
School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, PR China; College of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine, Shaanxi University of Chinese Medicine, Xianyang 712046, PR China; Key Laboratory of Pharmacodynamics and Material Basis of Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xi'an 712046, PR China; Shaanxi Key Laboratory of Research and Application of"Taibai Qi Yao", Xianyang 712046, PR China. Electronic address:
Article Synopsis
- Schisandra sphenanthera, a fruit used in traditional medicine, is reported to have beneficial effects on diabetes mellitus (DM) by helping with symptoms like prolonged cough and thirst and may aid in diabetes prevention and control.
- The research aims to uncover how Schisandra Sphenanthera (SDP) works against type 2 diabetes mellitus (T2DM) through various scientific methods like biochemical analysis and metabolite assays.
- Findings reveal that SDP can lower blood glucose levels, improve metabolic functions, and activate specific signaling pathways, ultimately leading to therapeutic effects on T2DM and restoring damage in organs like the liver and pancreas.
Application of machine learning and neural network models based on experimental evaluation of dissimilar resistance spot-welded joints between grade 2 titanium alloy and AISI 304 stainless steel.
Heliyon
December 2024
Department of Manufacturing Processes and Production Engineering, Rzeszow University of Technology, al. Powst. Warszawy 8, 35-959, Rzeszów, Poland.
The use of a composite welded joint consisting of titanium and austenitic stainless steel metals is evidently a favourable selection for industrial applications employing the resistance spot welding (RSW) operation. Nevertheless, achieving a high-quality welded joint proved challenging owing to the properties of the diverse range of materials' used. To improve the quality of dissimilar welded joints, the welding parameters should be selected precisely.
View Article and Find Full Text PDFWhy does the brain matter for education?
Br J Educ Psychol
December 2024
Centre for Educational Neuroscience, University of London, London, UK.
Background: The present special issue on mind, brain and education (educational neuroscience) contains four papers that employ a neuroscience-informed approach to educational phenomena, including dyslexia, academic self-concepts, bullying and the effect of mindset on learning.
Aim: This commentary positions the papers with respect to the goals and methods of educational neuroscience, placing them on a continuum of approaches from basic research to applied intervention.
Procedure: We argue that a focus on the brain matters for teachers because it increases understanding of how learning works and the factors that influence learning outcomes and student well-being without being reductionist.
Microstate analysis reveals the temporal alignment of mirroring and mentalizing systems.
Soc Neurosci
June 2024
Department of Psychiatry, BC Mental Health and Addictions Research Institute, University of British Columbia, Vancouver, BC, Canada.
The aim of the study is to understand how Mirror Neuron System (MNS) and Mentalizing Network (MZN) interact with each other. EEG data was collected during a photo judgment task with pictures of actions or facial expressions. Participants ( = 30, 63% women) were asked to either identify how the shown action/expression was being performed (MNS) or what the goal or intention behind the action was (MZN).
View Article and Find Full Text PDFEffects of forage feeding level on ruminal pH and metabolic adaptation of the rumen epithelium in pre-weaned Jersey calves.
Vet Anim Sci
December 2024
Department of Animal, Veterinary and Food Science, University of Idaho, Moscow, 83844, United States.
The objective of this study was to determine the effect of limiting forage provision in pre-weaned calves on ruminal pH and short chain fatty acid (SCFA) transport capacity during the pre-weaning period. Twelve Jersey bull calves (age = 1.9 ± 0.
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