AI Article Synopsis

  • Periodic and paroxysmal EEG patterns are common and often linked to specific neurological or systemic disorders.
  • A reclassification of these EEG patterns is proposed, focusing on their localization (generalized or focal) and periodicity (long or short), as highlighted by the original work of J. Gaches.
  • Specific patterns, such as suppression bursts and periodic lateralized epileptiform discharges, are associated with conditions like post-anoxic encephalopathies, drug-induced comas, and various neurological diseases, indicating a need for further examination of their clinical significance.

Article Abstract

Periodic and paroxysmal EEG patterns are frequent and easily recognized. They often correlate with particular neurological or systemic conditions. We propose a reclassification and critical examination of these periodic EEG patterns by reviewing the original work presented by J. Gaches in this journal some thirty years ago. Periodic EEG activity is still classified by its localisation--generalised or focal--and by its periodicity--long or short. Periodic long-interval diffuse paroxysmal patterns are reported with rare pathologies such as SSPE, trypanosomiasis or intoxication with phencyclidine. Suppression bursts (SB) may be found in two main situations post-anoxic encephalopathies and drug-induced comas. Ohtahara syndrome is a very rare childhood epileptic syndrome with SB. Periodic short-interval diffuse pattern have been reported in Creutzfeldt-Jakob disease but also in toxic encephalopathies, such as lithium intoxication or as recently reported in acute Cefepime intoxication as well as with metabolic encephalopathies and rarely during AIDS. Periodic lateralized epileptiform discharges (PLEDs) have been classified according to their morphology and the associated condition (epileptic seizures, subtle status, "vascular" seizure). The principal etiology is cerebro-vascular disease and herpes encephalitis but it has also been reported in several other neurological diseases.

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http://dx.doi.org/10.1016/s0987-7053(01)00288-xDOI Listing

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