Background: Accurate, rapid detection of atrial tachyarrhythmias has important implications in the use of implantable devices for treatment of cardiac arrhythmia. Currently available detection algorithms for atrial tachyarrhythmias, which use the single-index method, have limited sensitivity and specificity.
Methods And Results: In this study, we evaluated the performance of a new Bayesian discriminator algorithm in the detection of atrial fibrillation (AF), atrial flutter (AFL), and sinus rhythm (SR). Bipolar recording of 364 rhythms (AF=156, AFL=88, SR=120) at the high right atrium were collected from 20 patients who underwent electrophysiological procedures. After initial signal processing, a column vector of 5 features for each rhythm were established, based on the regularity, rate, energy distribution, percent time of quiet interval, and baseline reaching of the rectified autocorrelation coefficient functions. Rhythm identification was obtained by use of Bayes decision rule and assumption of Gaussian distribution. For the new Bayesian discriminator, the overall sensitivity for detection of SR, AF, and AFL was 97%, 97%, and 94%, respectively; and the overall specificity for detection of SR, AF, and AFL was 98%, 98%, and 99%, respectively. The overall accuracy of detection of SR, AF, and AFL was 98%, 97% and 98%, respectively. Furthermore, sensitivity, specificity, and accuracy of this algorithm were not affected by a range of white Gaussian noises with different intensities.
Conclusions: This new Bayesian discriminator algorithm, based on Bayes decision of multiple features of atrial electrograms, allows rapid on-line and accurate (98%) detection of AF with robust anti-noise performance.
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http://dx.doi.org/10.1161/01.cir.0000012349.14270.54 | DOI Listing |
Sci Rep
December 2024
School of Mechanical and Electrical Engineering, Qiqihar University, Qiqihar, 161006, China.
A prediction model of the pig house environment based on Bayesian optimization (BO), squeeze and excitation block (SE), convolutional neural network (CNN) and gated recurrent unit (GRU) is proposed to improve the prediction accuracy and animal welfare and take control measures in advance. To ensure the optimal model configuration, the model uses a BO algorithm to fine-tune hyper-parameters, such as the number of GRUs, initial learning rate and L2 normal form regularization factor. The environmental data are fed into the SE-CNN block, which extracts the local features of the data through convolutional operations.
View Article and Find Full Text PDFIndian J Ophthalmol
December 2024
Department of Ophthalmology, Yenepoya Deemed University, Karnataka, India.
Background/aims: India's linguistic and cultural diversity necessitates a region-specific validated Visual Functioning Questionnaire. The objective of this study was to translate the Indian Vision Function Questionnaire-33 (IND-VFQ-33) into the Kannada language and test its psychometric properties, underlying factor structure, and model fit.
Methods: A cross-sectional study was conducted among 330 participants, and basic psychometric properties (reliability, convergent, discriminant, construct validity, responsiveness, etc.
Rapid Commun Mass Spectrom
March 2025
School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham, UK.
Rationale: The analysis of natural abundance isotopes in biogenic NO molecules provides valuable insights into the nature of their precursors and their role in biogeochemical cycles. However, current methodologies (for example, the isotopocule map approach) face limitations, as they only enable the estimation of combined contributions from multiple processes at once rather than discriminating individual sources. This study aimed to overcome this challenge by developing a novel methodology for the partitioning of NO sources in soil, combining natural abundance isotopes and the use of a N tracer (N Gas Flux method) in parallel incubations.
View Article and Find Full Text PDFFront Pain Res (Lausanne)
December 2024
Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.
The sensory/discriminative domain of pain is often given more consideration than the cognitive and affective influences that ultimately make pain what it is: a highly subjective experience that is based on an individual's life history and experiences. While many investigations of the underlying mechanisms of pain have focused on solely noxious stimuli, few have compared somatosensory stimuli that cross the boundary from innocuous to noxious. Of those that have, there is little consensus on the similarities and differences in neural signaling across these sensory domains.
View Article and Find Full Text PDFFront Cardiovasc Med
December 2024
Department of Vascular Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Objective: To develop and validate a new prediction model based on the Lass-logistic regression with inflammatory serologic markers for the assessment of carotid plaque stability, providing clinicians with a reliable tool for risk stratification and decision-making in the management of carotid artery disease.
Methods: In this study, we retrospectively collected the data of the patients who underwent carotid endarterectomy (CEA) from 2019 to 2023 in Nanjing Drum Tower Hospital. Demographic characteristics, vascular risk factors, and the results of preoperative serum biochemistry were measured and collected.
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