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Article Synopsis
  • Innate immunity is the body's first line of defense against Mycobacterium tuberculosis, crucial for preventing infection from taking hold.
  • Pattern recognition receptors (PRRs) and various soluble and cell surface factors help identify and combat M. tuberculosis, but they can also contribute to disease severity.
  • Innate immunity not only responds early to infections but also sets the stage for the adaptive immune response, which plays a role in controlling the infection and may lead to latent TB.
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(Mtb) is an etiologic pathogen of human tuberculosis (TB), a serious infectious disease with high morbidity and mortality. In addition, the threat of drug resistance in anti-TB therapy is of global concern. Despite this, it remains urgent to research for understanding the molecular nature of dynamic interactions between host and pathogens during TB infection.

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Mycobacterium mucogenicum bacteremia: major role of clinical microbiologists.

BMC Infect Dis

December 2018

Service Universitaire des Maladies Infectieuses et du voyageur, Centre Hospitalier Dron, 135 avenue du Président Coty, 59200, Tourcoing, France.

Introduction: Mycobacterium mucogenicum is a rare but emerging cause of infections, especially in immunocompromised patients.

Case Presentation: We describe a new case of M. mucogenicum catheter-related bloodstream infection in a 34-year-old woman with ovarian cancer.

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Global efforts to eliminate tuberculosis by 2050 continue to challenge health systems. In countries with low reported tuberculosis incidence, such as the USA (3.1/100,000 population) and Cuba (6.

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