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Frailty Screening Using the Risk Analysis Index: A User Guide.
Jt Comm J Qual Patient Saf
December 2024
The Risk Analysis Index (RAI) has emerged as the most thoroughly validated and flexible assessment of surgical frailty, proven feasible for at-scale bedside screening and available in a suite of tools, that effectively risk stratifies patients across a wide variety of clinical contexts and data sources. This user guide provides a definitive summary of the RAI's theoretical model, historical development, validation, statistical performance, and clinical interpretation, placing the RAI in context with other frailty assessments and emphasizing some of its advantages. Detailed instructions are provided for each RAI variant, along with a systematic review of existing RAI-related literature.
View Article and Find Full Text PDFCharacterization of Culicoides and mosquito fauna at the National Zoological Garden of Rabat, Morocco.
Vet Parasitol Reg Stud Reports
January 2025
CIRAD, UMR ASTRE, F-34398 Montpellier, France; ASTRE, Univ Montpellier, CIRAD, INRAE, Montpellier, France. Electronic address:
Zoos are considering to be essential places for the conservation of wild animal species. It is essential to prevent their infection by pathogens especially for those belonging to threatened or extinct species. Zoo captive animals are susceptible to several Culicoides and mosquito borne-viruses.
View Article and Find Full Text PDFCurative and preemptive treatment of amputee pain by targeted muscle reinnervation: experience from a French military trauma center.
Eur J Trauma Emerg Surg
January 2025
Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, 101 Avenue Henri Barbusse, Clamart, 92140, France.
Introduction: Targeted muscle reinnervation (TMR) is a technique that has proven effective for the treatment and prevention of chronic pain following amputation, though its adoption remains limited. The authors report on their initial experience using TMR.
Methods: A prospective study was conducted in a military trauma center involving traumatic amputees treated with either curative or preemptive TMR.
Safety, Tolerability, and Immunogenicity of the Invaplex Vaccine Co-Administered with the dmLT Adjuvant in Dutch and Zambian Adults: Study Protocol for a Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Phase Ia/b Clinical Trial.
Vaccines (Basel)
January 2025
Leiden University Center for Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Background: Shigella infections remain endemic in places with poor sanitation and are a leading cause of diarrheal mortality globally, as well as a major contributor to gut enteropathy and stunting. There are currently no licensed vaccines for shigellosis but it has been estimated that an effective vaccine could avert 590,000 deaths over a 20-year period. A challenge to effective Shigella vaccine development has been the low immunogenicity and protective efficacy of candidate Shigella vaccines in infants and young children.
View Article and Find Full Text PDFCoupling of Li-Fe: Li Isotope Fractionation during Sorption onto Fe-Oxides.
ACS Earth Space Chem
January 2025
Department of Earth Sciences, Utrecht University, 3584 CB Utrecht, The Netherlands.
Chemical weathering processes play a key role in regulating the global climate over geological time scales. Lithium (Li) isotope compositions have proven to be a robust proxy for tracing weathering processes that produce secondary minerals, such as clays and oxides, with a focus often placed on Li adsorption to, or incorporation into, clay minerals. In addition, the interaction between Li and Fe-oxides has long been assumed and discussed based on field observations, but experimental constraints on this process are lacking.
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