Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity.

Microbes Infect

Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5802, USA.

Published: March 2002

Antimicrobial peptides are important host-defense molecules of innate immunity. Cathelicidins are a diverse family of potent, rapidly acting and broadly effective antimicrobial peptides, which are produced by a variety of cells. This review examines the classification, antimicrobial spectrum, mechanism of action, and regulation of cathelicidins.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1286-4579(02)01549-6DOI Listing

Publication Analysis

Top Keywords

innate immunity
8
antimicrobial peptides
8
cathelicidins microbicidal
4
microbicidal activity
4
activity mechanisms
4
mechanisms action
4
action roles
4
roles innate
4
immunity antimicrobial
4
peptides host-defense
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!