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Hidradenitis suppurativa: Clinical characteristics and determinants of treatment efficacy.
Dermatol Ther
September 2019
Ankara University, Faculty of Medicine, Dermatology and Venereology Department, Ankara, Turkey.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder that causes a significant decline in quality of life. There are numerous treatment options; however, real-life data on the efficacy of these treatments is limited. This study was performed in two centers to describe clinical characteristics and assess treatment outcome in a cohort of 139 patients with HS.
View Article and Find Full Text PDFInfluence of the retinoid acitretin on erythrocyte microrheology in vitro.
Int J Clin Pharmacol Ther
December 2006
Department of Biophysics, Collegium Medicum Nicolaus Copernicus University, Bydgoszcz, Poland.
Objective: To determine in vitro changes in the microrheology of red blood cells (RBCs) treated with acitretin (Ro 10-1670).
Volunteers And Methods: Venous blood samples were obtained from 27 healthy donors. Washed erythrocytes (5 x 10(6) cells/ml) were incubated for 30 min at 37 degrees C in solutions of low (25 ng/ml) and high (400 ng/ml) acitretin concentration.
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