The beta-lactamase gene blaA(BPS) in Burkholderia pseudomallei was cloned and expressed in Escherichia coli. BPS-1 is a cephalosporinase with an isoelectric point of 7.7. Sequence analysis of BPS-1 revealed conserved motifs typical of class A beta-lactamases and a relationship to the PenA (in B. cepacia) and BlaI (in Yersinia enterocolitica) lineages.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127091 | PMC |
| http://dx.doi.org/10.1128/AAC.46.4.1132-1135.2002 | DOI Listing |
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