Background: Trichilemmal carcinoma is an uncommon cutaneous neoplasm found primarily on the sun-exposed skin of the elderly.
Objective: To report a case of trichilemmal carcinoma presenting as a forehead nodule in an African American patient.
Methods: Case report and review of the literature.
Results: Our patient is the first reported case in the English language literature of trichilemmal carcinoma in an African American individual with skin phototype VI.
Conclusion: The occurrence of trichilemmal carcinoma in our African American patient suggests the diagnosis of trichilemmal carcinoma be added to the differential diagnosis of a nodule on the head region in this patient population.
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http://dx.doi.org/10.1046/j.1524-4725.2002.01128.x | DOI Listing |
Virchows Arch
January 2025
Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, 37044, Tours, France.
A case of cutaneous adnexal neoplasm with unusual squamoid morphology and harboring an in frame ACTB::ZMIZ2 fusion transcript was recently described. Herein, we report a second case of adnexal carcinoma harboring similar morphology and an identical in frame ACTB::ZMIZ2 fusion transcript. This 2.
View Article and Find Full Text PDFDermatol Reports
November 2024
Plastic Surgery Unit, Department of Neuroscience, University of Padua.
Keratitis-ichthyosis-deafness syndrome (KID) is a rare genetic disorder characterized by the triad of hyperkeratosis, ichthyosis, and congenital prelingual sensorineural deafness, with less than 100 cases described in the literature. In addition to many other extra-cutaneous manifestations, these patients are burdened by two principal increased risk factors involving the skin: the risk of developing infections and the risk of developing malignant skin tumors, especially Squamous Cell Carcinoma and Trichilemmal tumors. We present the case of a 7-year-old girl with a unique genetic variant described to date, who developed 4 dyskeratotic neoformation.
View Article and Find Full Text PDFDermatopathology (Basel)
December 2024
Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
Malignant proliferating trichilemmal tumors (MPTTs), arising from the external root sheath of hair follicles, are exceptionally rare, with limited documentation of their genetic alterations. We present a case of a 64-year-old African American woman who initially presented with a gradually enlarging nodule on her posterior scalp. An initial biopsy at an outside hospital suggested metastatic adenocarcinoma or squamous cell carcinoma (SCC) of an uncertain origin.
View Article and Find Full Text PDFFront Oncol
November 2024
Department of Dermatology, Second Affiliated Hospital of Jilin University, Changchun, China.
Trichilemmal carcinoma is an extremely rare malignant cutaneous tumor derived from the outer root sheath of the hair follicles, which most commonly occurs in the sun-exposed areas of elderly individuals. This article introduces a case of trichilemmal carcinoma that occurred on the scalp of a 36-year-old male patient, the first case reported and treated with surgical excision combined with photodynamic therapy.
View Article and Find Full Text PDFCureus
November 2024
General Surgery, Malavya Hospital, Bengaluru, IND.
A 54-year-old male with a past history of acute pancreatitis and pulmonary embolism presented with a scalp tumor in the occipital region for a six-month duration. With a biopsy report of squamous cell carcinoma, wide local excision with the lower island trapezius myocutaneous flap with skin grafting was done. However, the final pathology report revealed a proliferating trichilemmal tumor with clear margins.
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