Background: Melanosis is a rare, but well recognized late complication of some cases of metastatic melanoma. The precise pathogenesis is unclear. Most described cases report diffuse metastases and diffuse melanosis.
Objective: To present a case of localized melanosis secondary to locally metastatic melanoma without evidence of systemic involvement in a renal transplant patient.
Methods: Case report and literature review.
Results: We describe a case of localized melanosis in an immunocompromised patient without evidence of systemic metastases. The patient underwent limb perfusion and her immunosuppressive therapy has been stopped. The melanosis has not regressed; however, there has been no systemic involvement and her transplanted kidney is still functioning well.
Conclusion: To our knowledge this is the first report of this phenomenon in an immunocompromised host.
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| http://dx.doi.org/10.1046/j.1524-4725.2002.01139.x | DOI Listing |
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