A hydrodynamic characteristic performance of a three phase fluidised bed bioreactor has been studied with brewery wastewater. The influence of operating parameters, such as phase hold up, phase mixing, aspect ratio and superficial gas velocity, on an aerobic biodegradation in a bioreactor of 0.16 m i.d. and 2.7m in height, was analysed. A low-density (960 kg/m(3)) support particle with an internal interstice was employed. The particle and liquid loading were varied in order to determine the effect of phase hold up on bed homogeneity. The ranges in which particle loading and bed height affect fluidisation, and consequently chemical oxygen demand (COD) reduction, were determined. The distributor used in this work was designed such that fluid flow pattern similar to that of a draft tube was induced in the reactor. The low-density particles enabled cost effective operation at a relatively low gas superficial velocity (2.5 cm/s). Aspect ratio significantly influenced the overall bed homogeneity, and the optimum aspect ratio was 10, with volume of the support particles being 21% of the reactor volume.
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Sci Data
January 2025
Federal University of Bahia, Institute of Computing, Salvador, 40170-110, Brazil.
Multiple Myeloma (MM) is a cytogenetically heterogeneous clonal plasma cell proliferative disease whose diagnosis is supported by analyses on histological slides of bone marrow aspirate. In summary, experts use a labor-intensive methodology to compute the ratio between plasma cells and non-plasma cells. Therefore, the key aspect of the methodology is identifying these cells, which relies on the experts' attention and experience.
View Article and Find Full Text PDFJ Neuroradiol
January 2025
Department of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japan.
Introduction: Our previous work demonstrated that evaluating large ischemic cores using the apparent diffusion coefficient (ADC) could predict EVT outcomes, with the most frequent ADC (peak ADC) ≥520×10 mm/s associated with better clinical results. Since the degree of ADC reduction reflects the severity of ischemic stress, this study aimed to assess the utility of an ADC color map in visualizing this stress.
Patients And Methods: This retrospective cohort study included consecutive patients with a low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) using diffusion-weighted imaging (DWI) who underwent successful EVT recanalization between April 2014 and March 2023.
Neurology
February 2025
Department of Neurology, Department of Stroke, University Hospital Cleveland Medical Center, Case Western Reserve University, Cleveland, OH.
Background And Objectives: Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes in patients with e-ICA occlusion and large ischemic core infarcts treated with EVT vs medical management (MM).
Methods: This was a secondary analysis of the SELECT2 trial, a randomized controlled trial conducted at 31 international sites.
Matern Child Health J
January 2025
Department of Epidemiology and Biostatistics, Michigan State University, Fee Hall West Wing; 909 Wilson Rd, East Lansing, MI, 48824, USA.
Background: Dental care before pregnancy is critical for preventing poor oral health, which is associated with adverse pregnancy outcomes. People with low incomes, however, may face insurance-related barriers to obtaining dental care. Medicaid expansion under the Affordable Care Act increased access to dental care utilization among adults with low incomes.
View Article and Find Full Text PDFbioRxiv
January 2025
Department of Chemistry, 409 McCormick Road, University of Virginia, Charlottesville, VA 22904.
Antibody production is central to protection against new pathogens and cancers, as well as to certain forms of autoimmunity. Antibodies often originate in the lymph node (LN), specifically at the extrafollicular border of B cell follicles, where T and B lymphocytes physically interact to drive B cell maturation into antibody-secreting plasmablasts. In vitro models of this process are sorely needed to predict aspects of the human immune response.
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