The use of intermittent pneumatic compression boots to reduce the risk of deep venous thrombosis is contraindicated in patients with congestive heart failure (CHF) due to a theoretical increase in venous return to the heart and exacerbation of heart failure. This study evaluates intermittent pneumatic compression effects on pulmonary artery catheter parameters in CHF patients. We conducted a prospective within-patient study of CHF patients monitored by pulmonary artery catheterization. Hemodynamic variables were assessed with and without the use of intermittent pneumatic compression boots. A sample size of 18 patients was calculated a priori to obtain an 80 per cent power to detect a mean difference of 10 per cent. Twenty patients were studied; no patient suffered hemodynamic instability during the application of pneumatic compression; no statistically significant change in any hemodynamic parameters was noted. A trend toward decreasing mean arterial blood pressure (P = 0.057), pulmonary artery wedge pressure (P = 0.065), and systemic vascular resistance (P = 0.08) was observed. None were clinically significant. The application of intermittent pneumatic compression to the feet of patients in CHF does not significantly alter central hemodynamic parameters in CHF patients. This study suggests that intermittent pneumatic compression may be used in CHF patients for venous thromboembolic risk reduction.
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Pract Radiat Oncol
December 2024
Department of Radiation Oncology, Willis Knighton Cancer Center, 2600 Kings Highway, Shreveport, Louisiana, USA 71103 &, Department of Clinical Research, University of Jamestown, Fargo, ND, USA. Electronic address:
Purpose: Motion management presents a significant challenge in thoracic stereotactic ablative radiotherapy (SABR). Currently, a 5.0 mm standard planning target volume (PTV) margin is widely used to ensure adequate dose to the tumor.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Graduate School of Biomedical Engineering, Faculty of Engineering, and Tyree Institute of Health Engineering (IHealthE), UNSW Sydney, Kensington Campus, Sydney, NSW, 2052, Australia.
Hemodynamic stabilization is crucial in managing acute cardiac events, where compromised blood flow can lead to severe complications and increased mortality. Conditions like decompensated heart failure (HF) and cardiogenic shock require rapid and effective hemodynamic support. Current mechanical assistive devices, such as intra-aortic balloon pumps (IABP) and extracorporeal membrane oxygenation (ECMO), offer temporary stabilization but are limited to short-term use due to risks associated with prolonged blood contact.
View Article and Find Full Text PDFVopr Kurortol Fizioter Lech Fiz Kult
December 2024
National Medical Research Center for Rehabilitation and Balneology, Moscow, Russia.
Unlabelled: Lymphedema is a chronic disabling disease that affects 250 million people worldwide. To this date, it has been proven that treatment of this category of patients should be truly integrated - combining surgical, therapeutic methods and recovery procedures.
Objective: To study the influence of intermittent pneumatic compression (IPC) on microvasculature in patients with lymphedema of the lower extremities.
Phlebology
December 2024
Physical Medicine and Rehabilitation, University of Health Sciences, Başakşehir Çam and Sakura City Hospital, İstanbul, Türkiye.
Introduction: The increasing reliance on Internet search engines for health-related queries requires a thorough evaluation of the public's engagement with medical information. This study aims to analyze global trends in interest in lymphedema over the past decade using Google Trends (GT).
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Adv Sci (Weinh)
December 2024
Anatomy and Regenerative Medicine Institute (REMEDI), School of Medicine, College of Medicine Nursing and Health Sciences, University of Galway, Galway, H91 W2TY, Ireland.
Therapeutic proteins, the fastest growing class of pharmaceuticals, are subject to rapid proteolytic degradation in vivo, rendering them inactive. Sophisticated drug delivery systems that maintain protein stability, prolong therapeutic effects, and reduce administration frequency are urgently required. Herein, a mechanoresponsive hydrogel is developed contained within a soft robotic drug delivery (SRDD) device.
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